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Rabbit Anti-P2RX7/FITC

发布时间：2025/4/11 18:41:03 阅读次数：17

Rabbit Anti-P2RX7/FITC

Cat. Number：GV-12106R-FITC Quantity size：100ul

Concentration：1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50%

Glycerol.

Background：The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

Also known as：ATP receptor; P2X purinoceptor 7; P2X7; P2Z receptor; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel 7; P2RX7_HUMAN.

Specificity： ●Rabbit Polyclonal IgG, affinity purified by Protein A.

●Reacts with： Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, .

●Immunogen： KLH conjugated synthetic peptide derived from human P2RX7

(115-160aa).

●Predicted Molecular Weight： 69kDa.

Storage：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 ° C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.