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细胞色素P450 8B1抗体说明书

发布时间：2025/4/18 10:34:47 阅读次数：10

产品编号：JW-14165R

英文名称：CYP8B1 Rabbit pAb

中文名称：细胞色素P450 8B1抗体

英文别名：7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; CP8B1_HUMAN; CYP12; CYP8B1; CYPVIIIB1; Cytochrome P450 8B1; Cytochrome P450, family 8, subfamily B, polypeptide 1; Sterol 12-alpha-hydroxylase.

产品应用：WB, IHC-P, IHC-F, ICC, IF, ELISA

交叉反应：Human, Mouse (predicted: Sheep, Cow, Horse)

抗体来源：Rabbit

免疫原：KLH conjugated synthetic peptide derived from human CYP8B1: 151-250/501

亚型：IgG

性状：Liquid

纯化方法：affinity purified by Protein A

克隆类型：Polyclonal

理论分子量：58 kDa

浓度：1mg/ml

储存液：0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

亚细胞定位：Endoplasmic reticulum membrane. Microsome membrane.

组织特异性：Liver.

相似性：Belongs to the cytochrome P450 family.

SWISS：Q9UNU6

Gene ID：1582

功能：Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.

保存条件：Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.