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葡萄糖合成酶2抗体说明书

发布时间：2025/4/18 10:40:15 阅读次数：19

产品编号：JW-3989R

英文名称：Glycogen synthase 2 Rabbit pAb

中文名称：葡萄糖合成酶2抗体

英文别名：Glycogen starch synthase liver; Glycogen starch synthase liver; EC 2.4.1.11; Glycogen synthase 2 liver; GYS2; GYS2_HUMAN.

产品应用：WB, IHC-P, IHC-F, IF, ELISA

交叉反应：Mouse (predicted: Human, Rat, Rabbit, Pig, Dog, Horse)

抗体来源：Rabbit

免疫原：KLH conjugated synthetic peptide derived from human Glycogen synthase 2: 621-703/703

亚型：IgG

性状：Liquid

纯化方法：affinity purified by Protein A

克隆类型：Polyclonal

理论分子量：81 kDa

浓度：1mg/ml

储存液：0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

翻译后修饰：Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme (By similarity).

疾病：Defects in GYS2 are the cause of glycogen storage disease type 0 (GSD0) [MIM:240600]; A metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood, high blood ketones and low alanine and lactate concentrations. Although feeding relieves symptoms, it often results in postprandial hyperglycemia and hyperlactatemia.

相似性：Belongs to the glycosyltransferase 3 family.

SWISS：P54840

Gene ID：2998

功能：Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

保存条件：Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.