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AMG-337说明书

发布时间：2025/4/25 16:19:55 阅读次数：9

Product Specification Small Molecule Compounds

产品信息/Product information

产品货号/Cat No：IA3280

CAS No：1173699-31-4

英文名称/English Name：AMG-337

保存/Storage ：Powder:-20℃,2 years;In solvent(母液):-20℃,1 month;-80℃,6 months

化学属性/Chemical properties

分子式/Formula ：C₂3H₂2FN₇O₃

分子量/Molecular Wt： 463.46

外观/Appearance： White to off-white Solid

纯度/Purity ：≥98%

生物活性/Biological activity

产品描述/Description：是一种有效的高度选择性的ATP 竞争性MET 激酶抑制剂。(It is a potent and highly selective ATP-competitive MET kinase inhibitor.)

靶点/Target：c-Met

通路/Pathway：Protein Tyrosine Kinase/RTK

In Vitro:
Soluble in DMSO

"≥"means soluble,but saturation unknown
*配成工作液后，建议立即使用，尽快用完。
*产品为非无菌包装，请根据实验需求提前做好预处理。如需配成储备液，建议分装保存，避免反复冻融造成的产品
失效。
*The product is non-sterile packaging.please do pre-treatment in advance according to experimental needs.If it is necessary to prepare a stock solution,it is recommended to store in aliquots to avoid product failure caused by repeated freezing and
thawing.

溶液制备参考/Solution preparation reference

Mass

Solvent

Concentration      1mg                5mg                10mg

1mM              2.1577mL    10.7884mL    21.5768mL
5mM                0.4315mL    2.1577mL        4.3154mL
10mM             0.2158mL    1.0788mL       2.1577mL