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晚期糖基化终末产物抗体

发布时间：2025/7/17 8:59:25 阅读次数：16

CAT#:GV-1158R-50ul
-20℃保存
晚期糖基化终末产物抗体

英文别名：advanced glycosylation end products; AGE.
产品应用：WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, Flow-Cyt=1ug/Test, IF=1:100-500, ELISA=1:5000-10000
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
交叉反应：Human, Mouse, Rat
抗体来源：Rabbit
免疫原：AGEs
亚型：IgG
性状：Liquid
纯化方法：affinity purified by Protein A
克隆类型：Polyclonal
理论分子量：62 kDa
浓度：1mg/ml
储存液：0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域：Cardiovascular > Blood > Serum Proteins
Developmental Biology > Lineage specification > Endoderm
Kits/ Lysates/ Other > Kits > ELISA Kits > ELISA Kits > Signal transduction proteins ELISA kits
Metabolism > Types of disease > Metabolic disorders
Signal Transduction > Metabolism > Lipid metabolism
Signal Transduction > Protein Trafficking > Chaperones > Other Chaperones
Stem Cells > Lineage Markers > Endoderm
亚细胞定位：Secreted.
组织特异性：Plasma.
翻译后修饰：Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.
疾病：Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
相似性：Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.
功能：Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
保存条件：Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.