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淋巴管内皮透明质酸受体重组兔单抗

发布时间：2025/7/18 10:06:58 阅读次数：72

产品编号：GV-52811R
产品类型：重组兔单抗
英文名称：LYVE1 Recombinant Rabbit mAb
中文名称：淋巴管内皮透明质酸受体重组兔单抗
英文别名：lymphalic vessel endotheilial hyaluronan receptor 1; CRSBP 1; CRSBP1; extracellular link domain containing 1; extracellular link domain-containing 1; HAR; hyaluronic acid receptor; Cell surface retention sequence-binding protein 1; CRSBP-1; extracellular link domain-containing 1; Extracellular link domain-containing protein 1; Lymphatic vessel endothelial hyaluronic acid receptor 1; LYVE1_HUMAN; Lymphatic endothelium specific hyaluronan receptor; LYVE 1; LYVE-1; XLKD1.
产品应用：IHC-P=1:50-200, IHC-F=1:50-200, Flow-Cyt=1:50, ICC/IF=1:50, IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
交叉反应：Human
抗体来源：Rabbit
免疫原：Recombinant human LYVE1 protein
亚型：IgG
性状：Size : 25ul/50ul/100ul
Liquid
Size : 200ug (PBS only)
Lyophilized
Note: Centrifuge tubes before opening. Reconstitute the lyophilized product in distilled water. Optimal concentration should be determined by the end user.
纯化方法：affinity purified by Protein A
克隆类型：Recombinant
克隆号：5C1
理论分子量：32 kDa
浓度：1mg/ml
储存液：Size : 25ul/50ul/100ul
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Size : 200ug (PBS only)
0.01M PBS
亚基：Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN.
亚细胞定位：Membrane; Single-pass type I membrane protein. Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
组织特异性：Restricted to tissues or cell lines expressing erythroid characters.
翻译后修饰：O-glycosylated.
相似性：Contains 1 Link domain.
SWISS：Q9Y5Y7
Gene ID：10894
功能：Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
保存条件：Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项：This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.