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Feline immunodeficiency virus complete genome
GenBank: M25381.1
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LOCUS FIVCG 9474 bp ss-RNA linear VRL 25-JUL-2016
DEFINITION Feline immunodeficiency virus complete genome.
ACCESSION M25381 M25729
VERSION M25381.1
KEYWORDS complete genome; env protein; gag protein; long terminal repeat;
pol protein.
SOURCE Feline immunodeficiency virus
ORGANISM Feline immunodeficiency virus
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
REFERENCE 1 (bases 1 to 355)
AUTHORS Olmsted,R.A., Barnes,A.K., Yamamoto,J.K., Hirsch,V.M., Purcell,R.H.
and Johnson,P.R.
TITLE Molecular cloning of feline immunodeficiency virus
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (7), 2448-2452 (1989)
PUBMED 2928341
REFERENCE 2 (bases 1 to 9472)
AUTHORS Talbott,R.L., Sparger,E.E., Lovelace,K.M., Fitch,W.M.,
Pedersen,N.C., Luciw,P.A. and Elder,J.H.
TITLE Nucleotide sequence and genomic organization of feline
immunodeficiency virus
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (15), 5743-5747 (1989)
PUBMED 2762293
REFERENCE 3 (bases 1 to 9474)
AUTHORS Olmsted,R.A., Hirsch,V.M., Purcell,R.H. and Johnson,P.R.
TITLE Nucleotide sequence analysis of feline immunodeficiency virus:
genome organization and relationship to other lentiviruses
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (20), 8088-8092 (1989)
PUBMED 2813380
REFERENCE 4 (bases 7175 to 7182)
AUTHORS Elder,J.H.
JOURNAL UnpublishedCOMMENT Original source text: Feline immunodeficiency virus (strain
Petaluma) (clone: 34TF10) cDNA to genomic RNA; and Feline
immunodeficiency virus (strain Petaluma) (clone: FIV-14) cDNA to
genomic RNA.
[4] revision.
[2] sequence kindly provided in computer-readable form by John
Elder, Scripps Institute, La Jolla, CA. [3] sequence kindly
provided in computer-readable form by Robert Olmstead, NIAID, NIH,
Bethesda, MD. [1] contains the LTR sequence from the complete
genome in [3].
The sequence from [3] is shown (with differences from [2]); the
substantive difference from [2] is at position 6123 where the
latter possesses an early stop codon in orf2, which is thought to
encode the transactivator protein. Clone 34TF10 is, nevertheless,
biologically active as described in [2]. A difference earlier
reported at 7175-7182 turns out to have been a typo [2,4]. Orf1 is
weakly homologous (PLSEARCH) with the Q orf of visna and has no
detectable similarity to the vif protein of HIV and SIV. This is
consistent with the clustering of FIV with the ungulate
lentiviruses [2],[3]. Several 'urfs' are identified by [2] and [3]
of which only orf3, possibly analogous to the L orf of visna, is
annotated below; a small, possibly associated, orf is found at
8955-9170. For a fuller discussion of the reading frames, see [2]
and [3].FEATURES Location/Qualifiers source 1..9474
/organism="Feline immunodeficiency virus"
/mol_type="genomic RNA"
/strain="Petaluma"
/db_xref="taxon:11673"
/clone="34TF10"
/clone="FIV-14"
repeat_region 1..355
/standard_name="5' LTR"
/rpt_type=long_terminal_repeat
variation 12
/citation=[2]
/replace="c"
variation 12
/citation=[3]
/replace="t"
variation 122
/citation=[3]
/replace="c"
variation 122
/citation=[2]
/replace="t"
variation 146
/citation=[3]
/replace="g"
variation 146
/citation=[2]
/replace="t"
repeat_region 217..281
/note="R repeat 5' copy"
misc_binding 357..377
/note="primer binding site"
/bound_moiety="unspecified"
variation 373..374
/note="replace (373,'a')"
/citation=[2]
variation 373..374
/note="replace (373,'ag')"
/citation=[3]
variation 498..501
/note="ggac in [3]; agca in [2]"
gene 628..1980
/gene="gag"
CDS 628..1980
/gene="gag"
/codon_start=1
/product="gag protein"
/protein_id="AAB59936.1"
/translation="MGNGQGRDWKMAIKRCSNVAVGVGGKSKKFGEGNFRWAIRMANV
STGREPGDIPETLDQLRLVICDLQERREKFGSSKEIDMAIVTLKVFAVAGLLNMTVST
AAAAENMYSQMGLDTRPSMKEAGGKEEGPPQAYPIQTVNGVPQYVALDPKMVSIFMEK
AREGLGGEEVQLWFTAFSANLTPTDMATLIMAAPGCAADKEILDESLKQLTAEYDRTH
PPDAPRPLPYFTAAEIMGIGLTQEQQAEARFAPARMQCRAWYLEALGKLAAIKAKSPR
AVQLRQGAKEDYSSFIDRLFAQIDQEQNTAEVKLYLKQSLSIANANADCKKAMSHLKP
ESTLEEKLRACQEIGSPGYKMQLLAEALTKVQVVQSKGSGPVCFNCKKPGHLARQCRE
VKKCNKCGKPGHVAAKCWQGNRKNSGNWKAGRAAAPVNQMQQAVMPSAPPMEEKLLDL
"
variation 1575
/gene="gag"
/note="g in [3]; a in [2]"
variation 1840
/gene="gag"
/note="g in [3]; c in [2]"
variation 1977
/gene="gag"
/note="a in [3]; g in [2]"
variation 2028
/note="g in [3]; a in [2]"
variation 2033
/note="c in [3]; t in [2]"
gene 2251..5243
/gene="pol"
CDS 2251..5243
/gene="pol"
/codon_start=3
/product="pol polyprotein"
/protein_id="AAB59937.1"
/translation="VLEDNSLIQPLLGRDNMIKFNIRLVMAQISDKIPVVKVKMKDPN
KGPQIKQWPLTNEKIEALTEIVERLEREGKVKRADPNNPWNTPVFAIKKKSGKWRMLI
DFRELNKLTEKGAEVQLGLPHPAGLQIKKQVTVLDIGDAYFTIPLDPDYAPYTAFTLP
RKNNAGPGRRFVWCSLPQGWILSPLIYQSTLDNIIQPFIRQNPQLDIYQYMDDIYIGS
NLSKKEHKEKVEELRKLLLWWGFETPEDKLQEEPPYTWMGYELHPLTWTIQQKQLDIP
EQPTLNELQKLAGKINWASQAIPDLSIKALTNMMRGNQNLNSTRQWTKEARLEVQKAK
KAIEEQVQLGYYDPSKELYAKLSLVGPHQISYQVYQKDPEKILWYGKMSRQKKKAENT
CDIALRACYKIREESIIRIGKEPRYEIPTSREAWESNLINSPYLKAPPPEVEYIHAAL
NIKRALSMIKDAPIPGAETWYIDGGRKLGKAAKAAYWTDTGKWQVMELEGSNQKAEIQ
ALLLALKAGSEEMNIITDSQYVINIILQQPDMMEGIWQEVLEELEKKTAIFIDWVPGH
KGIPGNEEVDKLCQTMMIIEGDGILDKRSEDAGYDLLAAKEIHLLPGEVKVIPTGVKL
MLPKGYWGLIIGKSSIGSKGLDVLGGVIDEGYRGEIGVIMINVSRKSITLMERQKIAQ
LIILPCKHEVLEQGKVVMDSERGDNGYGSTGVFSSWVDRIEEAEINHEKFHSDPQYLR
TEFNLPKMVAEEIRRKCPVCRIRGEQVGGQLKIGPGIWQMDCTHFDGKIILVGIHVES
GYIWAQIISQETADCTVKAVLQLLSAHNVTELQTDNGPNFKNQKMEGVLNYMGVKHKF
GIPGNPQSQALVENVNHTLKVWIRKFLPETTSLDNALSLAVHSLNFKRRGRIGGMAPY
ELLAQQESLRIQDYFSAIPQKLQAQWIYYKDQKDKKWKGPMRVEYWGQGSVLLKDEEK
GYFLIPRRHIRRVPEPCALPEGDE" variation 2288
/gene="pol"
/note="a in [3]; g in [2]" variation 2464
/gene="pol"
/note="g in [3]; a in [2]" variation 2490
/gene="pol"
/note="c in [3]; t in [2]" variation 2580
/gene="pol"
/note="c in [3]; t in [2]" variation 2631
/gene="pol"
/note="t in [3]; c in [2]" variation 2735
/gene="pol"
/note="a in [3]; g in [2]" variation 3733
/gene="pol"
/note="a in [3]; g in [2]" variation 3743
/gene="pol"
/note="a in [3]; t in [2]" variation 3812
/gene="pol"
/note="g in [3]; a in [2]" variation 4202
/gene="pol"
/note="g in [3]; a in [2]" variation 4211
/gene="pol"
/note="c in [3]; t in [2]" variation 4271
/gene="pol"
/note="c in [3]; t in [2]" variation 4493
/gene="pol"
/note="a in [3]; g in [2]" variation 4540
/gene="pol"
/note="g in [3]; t in [2]" variation 4706
/gene="pol"
/note="c in [3]; t in [2]" variation 4891
/gene="pol"
/note="g in [3]; a in [2]"
CDS 5236..5991
/note="ORF 1"
/codon_start=1
/protein_id="AAB59938.1"
/translation="MSEEDWQVSRRLFAVLQGGVNSAMLYISRLPPDEREKYKKDFKK
RLFDTETGFIKRLRKAEGIKWSFHTRDYYIGYVREMVAGSTTSLSLRMYIYISNPLWH
SQYRPGLKNFNKEWPFVNMWIKTGFMWDDIEKQNICIGGEVSPGWGPGMVGIAIKAFS
CGERKIEATPVMIIRGEIDPKKWCGDCWNLMCLRNSPPKTLQRLAMLACGVPAKKWRG
CCNQRFVSPYRTPADLEVIQSKPSWNLLWSGEL" variation 5332
/note="g in [3]; a in [2]" variation 5497
/note="t in [3]; c in [2]" variation 5559
/note="t in [3]; c in [2]" variation 5986
/note="t in [3]; c in [2]"
CDS 5992..6228
/note="ORF 2"
/codon_start=1
/protein_id="AAB59939.1"
/translation="MEDIIVLFNRVTEKLEKELAIRIFVLAHQLERDKAIRLLQGLFW
RYRFKKPRVDYCLCWWCCKFYYWQLQSTLSITTA" variation 6000
/note="c in [3]; a in [2]" variation 6123
/note="g in [3]; a in [2]" variation 6149
/note="t in [3]; c in [2]" variation 6179
/note="a in [3]; g in [2]" variation 6238
/note="g in [3]; t in [2]" variation 6245..6248
/note="attt in [3]; ttt in [2]"
gene 6266..8836
/gene="env"
CDS 6266..8836
/gene="env"
/codon_start=1
/product="envelope polyprotein"
/protein_id="AAB59940.1"
/translation="MAEGFAANRQWIGLEEAEELLDFDIATQMSEEGPLNPGVNPFRV
PGITEKEKQNYCNILQPKLQDLRNEIQEVKLEEGNAGKFRRARFLRYSDESVLSLVHA
FIGYCIYLGNRNKLGSLRHDIDIEAPQEECYNNREKGTTDNIKYGRRCCLGTVTLYLI
LFIGIIIYSQTTNAQVVWRLPPLVVPVEESEIIFWDCWAPEEPACQDFLGAMIHLKAK
TNISIREGPTLGNWAREIWATLFKKATRQCRRGRIWKRWNETITGPSGCANNTCYNVS
VIVPDYQCYLDRVDTWLQGKINISLCLTGGKMLYNKVTKQLSYCTDPLQIPLINYTFG
PNQTCMWNTSQIQDPEIPKCGWWNQMAYYNSCKWEEAKVKFHCQRTQSQPGSWFRAIS
SWKQRNRWEWRPDFESKKVKISLQCNSTKNLTFAMRSSGDYGEVTGAWIEFGCHRNKS
KLHAEARFRIRCRWNVGSNTSLIDTCGNTQKVSGANPVDCTMYSNKMYNCSLQNGFTM
KVDDLIMHFNMKKAVEMYNIAGNWSCTSDLPSSWGYMNCNCTNSSSSYSGTKMACPSN
RGILRNWYNPVAGLRQSLEQYQVVKQPDYLVVPEEVMEYKPRRKRAAIHVMLALAAVL
SIAGAGTGATAIGMVTQYHQVLATHQEAVEKVTEALKINNLRLVTLEHQVLVIGLKVE
AMEKFLYTAFAMQELGCNQNQFFCKIPPELWTRYNMTINQTIWNHGNITLGEWYNQTK
DLQQKFYEIIMDIEQNNVQGKKGIQQLQKWEDWVGWIGNIPQYLKGLLGGILGIGLGV
LLLILCLPTLVDCIRNCIHKILGYTVIAMPEVEGEEIQPQMELRRNGRQCGMSEKEEE
" variation 6306
/gene="env"
/note="t in [3]; c in [2]" variation 6430
/gene="env"
/note="c in [3]; t in [2]" variation 6548
/gene="env"
/note="a in [3]; c in [2]"
CDS 6712..6918
/gene="env"
/note="ORF 3"
/codon_start=1
/protein_id="AAB59941.1"
/translation="MLPRNGDFVPDFIYRNNNIFTDNQRSGSMETSTISSPSRRIRNN
FLGLLGTRRTRLSGLSWGNDTSKS" variation 6739
/gene="env"
/note="c in [3]; t in [2]" variation 6753
/gene="env"
/note="t in [3]; c in [2]" variation 6758
/gene="env"
/note="a in [3]; g in [2]" variation 6764
/gene="env"
/note="a in [3]; g in [2]" variation 6779
/gene="env"
/note="a in [3]; g in [2]" variation 6782..6783
/gene="env"
/note="aa in [3]; gg in [2]" variation 7175..7182
/gene="env"
/note="acaggagg in [3]; caggagga in [2]" variation 7381
/gene="env"
/note="a in [3]; g in [2]" variation 7484
/gene="env"
/note="g in [3]; a in [2]" variation 7512..7513
/gene="env"
/note="ag in [3]; ca in [2]" variation 7618
/gene="env"
/note="a in [3]; c in [2]" variation 7625
/gene="env"
/note="g in [3]; a in [2]" variation 7670
/gene="env"
/note="a in [3]; g in [2]" variation 7704..7708
/gene="env"
/note="aaaaa in [3]; caaat in [2]" variation 7750
/gene="env"
/note="t in [3]; c in [2]" variation 7808..7810
/gene="env"
/note="atg in [3]; gta in [2]" variation 7824..7828
/gene="env"
/note="aaaag in [3]; caaaa in [2]" variation 7996
/gene="env"
/note="g in [3]; a in [2]" variation 8054
/gene="env"
/note="g in [3]; c in [2]" variation 8129
/gene="env"
/note="g in [3]; a in [2]" variation 8222
/gene="env"
/note="g in [3]; a in [2]" variation 8238
/gene="env"
/note="a in [3]; g in [2]" variation 8329
/gene="env"
/note="g in [3]; a in [2]" variation 8377
/gene="env"
/note="t in [3]; c in [2]" variation 8394
/gene="env"
/note="c in [3]; t in [2]" variation 8548..8550
/gene="env"
/note="gaa in [3]; aac in [2]" variation 8588
/gene="env"
/note="g in [3]; a in [2]" repeat_region 9120..9474
/note="3' LTR"
/rpt_type=long_terminal_repeat variation 9131
/note="t in [3]; c in [2]" variation 9241
/note="c in [3]; t in [2]" variation 9265
/note="g in [3]; t in [2]" repeat_region 9336..9400
/note="R repeat 3' copy"ORIGIN 5' terminus of 5' LTR. 1 tgggatgagt attggaaccc tgaagaaata gaaagaatgc ttatggacta gggactgttt
61 acgaacaaat gataaaagga aatagctgag catgactcat agttaaagcg ctagcagctg
121 cctaaccgca aaaccacatc ctatggaaag cttgctaatg acgtataagt tgttccattg
181 taagagtata taaccagtgc tttgtgaaac ttcgaggagt ctctttgttg aggacttttg
241 agttctccct tgaggctccc acagatacaa taaatatttg agattgaacc ctgtcgagta
301 tctgtgtaat cttttttacc tgtgaggtct cggaatccgg gccgagaact tcgcagttgg
361 cgcccgaaca gggacttgat tgagagtgat tgaggaagtg aagctagagc aatagaaagc
421 tgttaagcag aactcctgct gacctaaata gggaagcagt agcagacgct gctaacagtg
481 agtatctcta gtgaagcgga ctcgagctca taatcaagtc attgtttaaa ggcccagata
541 aattacatct ggtgactctt cgcggacctt caagccagga gattcgccga gggacagtca
601 acaaggtagg agagattcta cagcaacatg gggaatggac aggggcgaga ttggaaaatg
661 gccattaaga gatgtagtaa tgttgctgta ggagtagggg ggaagagtaa aaaatttgga
721 gaagggaatt tcagatgggc cattagaatg gctaatgtat ctacaggacg agaacctggt
781 gatataccag agactttaga tcaactaagg ttggttattt gcgatttaca agaaagaaga
841 gaaaaatttg gatctagcaa agaaattgat atggcaattg tgacattaaa agtctttgcg
901 gtagcaggac ttttaaatat gacggtgtct actgctgctg cagctgaaaa tatgtattct
961 caaatgggat tagacactag gccatctatg aaagaagcag gtggaaaaga ggaaggccct
1021 ccacaggcat atcctattca aacagtaaat ggagtaccac aatatgtagc acttgaccca
1081 aaaatggtgt ccatttttat ggaaaaggca agagaaggac taggaggtga ggaagttcaa
1141 ctatggttta ctgccttctc tgcaaattta acacctactg acatggccac attaataatg
1201 gccgcaccag ggtgcgctgc agataaagaa atattggatg aaagcttaaa gcaactgaca
1261 gcagaatatg atcgcacaca tccccctgat gctcccagac cattacccta ttttactgca
1321 gcagaaatta tgggtatagg attaactcaa gaacaacaag cagaagcaag atttgcacca
1381 gctaggatgc agtgtagagc atggtatctc gaggcattag gaaaattggc tgccataaaa
1441 gctaagtctc ctcgagctgt gcagttaaga caaggagcta aggaagatta ttcatccttt
1501 atagacagat tgtttgccca aatagatcaa gaacaaaata cagctgaagt taagttatat
1561 ttaaaacagt cattgagcat agctaatgct aatgcagact gtaaaaaggc aatgagccac
1621 cttaagccag aaagtaccct agaagaaaag ttgagagctt gtcaagaaat aggctcacca
1681 ggatataaaa tgcaactctt ggcagaagct cttacaaaag ttcaagtagt gcaatcaaaa
1741 ggatcaggac cagtgtgttt taattgtaaa aaaccaggac atctagcaag acaatgtaga
1801 gaagtgaaaa aatgtaataa atgtggaaaa cctggtcatg tagctgccaa atgttggcaa
1861 ggaaatagaa agaattcggg aaactggaag gcggggcgag ctgcagcccc agtgaatcaa
1921 atgcagcaag cagtaatgcc atctgcacct ccaatggagg agaaactatt ggatttataa
1981 attataataa agtaggtact actacaacat tagaaaagag gccagaaata ctcatatttg
2041 taaatggata tcctataaaa tttttattag acacaggagc agatataaca attttaaata
2101 ggagagattt tcaagtaaaa aattctatag aaaatggaag gcaaaatatg attggagtag
2161 gaggaggaaa gagaggaaca aattatatta atgtacattt agagattaga gatgaaaatt
2221 ataagacaca atgtatattt ggtaatgttt gtgtcttaga agataactca ttaatacaac
2281 cattattagg gagagataat atgattaaat tcaatattag gttagtaatg gctcaaattt
2341 ctgataagat tccagtagta aaagtaaaaa tgaaggatcc taataaagga cctcaaataa
2401 aacaatggcc attaacaaat gaaaaaattg aagccttaac agaaatagta gaaagactag
2461 aaagagaagg gaaagtaaaa agagcagatc caaataatcc atggaataca ccagtatttg
2521 ctataaaaaa gaaaagtgga aaatggagaa tgctcataga ttttagagaa ttaaacaaac
2581 taactgagaa aggagcagag gtccagttgg gactacctca tcctgctggt ttacaaataa
2641 aaaaacaagt aacagtatta gatatagggg atgcatattt caccattcct cttgatccag
2701 attatgctcc ttatacagca tttactttac ctagaaaaaa taatgcggga ccaggaagga
2761 gatttgtgtg gtgtagtcta ccacaaggct ggattttaag tccattgata tatcaaagta
2821 cattagataa tataatacaa ccttttatta gacaaaatcc tcaattagat atttaccaat
2881 atatggatga catttatata ggatcaaatt taagtaaaaa ggagcataaa gaaaaggtag
2941 aagaattaag aaaattacta ttatggtggg gatttgaaac tccagaagat aaattacagg
3001 aagaaccccc atatacatgg atgggttatg aattacatcc attaacatgg acaatacaac
3061 agaaacagtt agacattcca gaacagccca ctctaaatga gttgcaaaaa ttagcaggaa
3121 aaattaattg ggctagccaa gctattccag acttgagtat aaaagcatta actaacatga
3181 tgagaggaaa tcaaaaccta aattcaacaa gacaatggac taaagaagct cgactggaag
3241 tacaaaaggc aaaaaaggct atagaagaac aagtacaact aggatactat gaccccagta
3301 aggagttata tgctaaatta agtttggtgg gaccacatca aataagttat caagtatatc
3361 agaaggatcc agaaaagata ctatggtatg gaaaaatgag tagacaaaag aaaaaggcag
3421 aaaatacatg tgatatagcc ttaagagcat gctataagat aagagaagag tctattataa
3481 gaataggaaa agaaccaaga tatgaaatac ctacttctag agaagcctgg gaatcaaatt
3541 taattaattc accatatctt aaggccccac ctcctgaggt agaatatatc catgctgctt
3601 tgaatataaa gagagcgtta agtatgataa aagatgctcc aataccagga gcagaaacat
3661 ggtatataga tggaggtaga aagctaggaa aagcagcaaa agcagcctat tggacagata
3721 caggaaagtg gcaagtgatg gaattagaag gcagtaatca gaaggcagaa atacaagcat
3781 tattattggc attaaaagca ggatcagagg agatgaatat tataacagat tcacaatatg
3841 ttataaatat tattcttcaa caaccagata tgatggaggg aatctggcaa gaagttttag
3901 aagaattgga gaagaaaaca gcaatattta tagattgggt cccaggacat aaaggtattc
3961 caggaaatga ggaagtagat aagctttgtc aaacaatgat gataatagaa ggggatggga
4021 tattagataa aaggtcagaa gatgcaggat atgatttatt agctgcaaaa gaaatacatt
4081 tattgccagg agaggtaaaa gtaataccaa caggggtaaa gctaatgttg cctaaaggat
4141 attggggatt aataatagga aaaagctcga tagggagtaa aggattggat gtattaggag
4201 gggtaataga cgaaggatat cgaggtgaaa ttggagtaat aatgattaat gtatcaagaa
4261 aatcaatcac cttaatggaa cgacaaaaga tagcacaatt aataatattg ccttgtaaac
4321 atgaagtatt agaacaagga aaagtagtaa tggattcaga gagaggagac aatggttatg
4381 ggtcaacagg agtattctcc tcttgggttg acagaattga ggaagcagaa ataaatcatg
4441 aaaaatttca ctcagatcca cagtacttaa ggactgaatt taatttacct aaaatggtag
4501 cagaagagat aagacgaaaa tgcccagtat gcagaatcag aggagaacaa gtgggaggac
4561 aattgaaaat agggcctggt atctggcaaa tggattgcac acactttgat ggcaaaataa
4621 ttcttgtggg tatacatgtg gaatcaggat atatatgggc acaaataatt tctcaagaaa
4681 ctgctgactg tacagttaaa gctgtcttac aattgttgag tgctcataat gttactgaat
4741 tacaaacaga taatggacca aattttaaaa atcaaaagat ggaaggagta ctcaattaca
4801 tgggtgtgaa acataagttt ggtatcccag ggaacccaca gtcacaagca ttagttgaaa
4861 atgtaaatca tacattaaaa gtttggattc ggaaattttt gcctgaaaca acctccttgg
4921 ataatgcctt atctctcgct gtacatagtc tcaattttaa aagaagaggt aggataggag
4981 ggatggcccc ttatgaatta ttagcacaac aagaatcctt aagaatacaa gattattttt
5041 ctgcaatacc acaaaaattg caagcacagt ggatttatta taaagatcaa aaagataaga
5101 aatggaaagg accaatgaga gtagaatact ggggacaggg atcagtatta ttaaaggatg
5161 aagagaaggg atattttctt atacctagga gacacataag gagagttcca gaaccctgcg
5221 ctcttcctga aggggatgag tgaagaagat tggcaggtaa gtagaagact ctttgcagtg
5281 ctccaaggag gagtaaatag cgctatgcta tacatatcta ggctacctcc ggatgaaaga
5341 gaaaagtata aaaaagactt caagaaaaga ctttttgaca cagaaacagg atttataaag
5401 agactacgga aagctgaagg aataaaatgg agctttcata ctagagatta ttacatagga
5461 tatgtcagag aaatggtggc aggatccact acatcattaa gtctaaggat gtatatatat
5521 ataagtaacc cactatggca ttctcagtat cgtccaggtt tgaaaaattt caataaggaa
5581 tggccttttg taaatatgtg gataaaaaca ggatttatgt gggatgatat tgaaaaacaa
5641 aatatttgta taggaggaga agtttcacca ggatggggac cagggatggt aggtatagca
5701 ataaaagctt ttagttgtgg cgaaagaaag attgaggcta ctcctgtaat gattataaga
5761 ggagaaatag atccaaaaaa atggtgcgga gattgttgga atttaatgtg tcttagaaac
5821 tcacctccaa agactttaca aagactcgct atgttggcgt gtggcgtgcc ggctaagaag
5881 tggcgaggat gctgtaatca acgctttgtt tctccttaca gaacgcctgc tgatttagag
5941 gtcattcaat ccaagcccag ctggaacctg ttatggtcgg gagaattatg aatggaagac
6001 ataatagtat tattcaatag ggtcactgag aaactagaaa aagaattagc tatcagaata
6061 tttgtattag cacatcaatt agaaagggac aaagctatta gattactaca aggattattt
6121 tggagatata gatttaagaa accccgagta gattattgtt tatgttggtg gtgttgcaaa
6181 ttctattatt ggcagttgca atctacatta tcaataacta ctgcttagaa atatttagat
6241 taatatttca tttgcaacaa taagaatggc agaaggattt gcagccaata gacaatggat
6301 aggactagaa gaagctgaag agttattaga ttttgatata gcaacacaaa tgagtgaaga
6361 aggaccacta aatccaggag taaacccatt tagggtacct ggaataacag aaaaagaaaa
6421 gcaaaactac tgtaacatat tacaacctaa gttacaagat ctaaggaacg aaattcaaga
6481 ggtaaaactg gaagaaggaa atgcaggtaa gtttagaaga gcaagatttt taaggtattc
6541 tgatgaaagt gtattgtccc tggttcatgc gttcatagga tattgtatat atttaggtaa
6601 tcgaaataag ttaggatctt taagacatga cattgatata gaagcacccc aagaagagtg
6661 ttataataat agagagaagg gtacaactga caatataaaa tatggtagac gatgttgcct
6721 aggaacggtg actttgtacc tgattttatt tataggaata ataatatatt cacagacaac
6781 caacgctcag gtagtatgga gacttccacc attagtagtc ccagtagaag aatcagaaat
6841 aattttttgg gattgttggg caccagaaga acccgcctgt caggactttc ttggggcaat
6901 gatacatcta aaagctaaga caaatataag tatacgagag ggacctacct tggggaattg
6961 ggctagagaa atatgggcaa cattattcaa aaaggctact agacaatgta gaagaggcag
7021 aatatggaaa agatggaatg agactataac aggaccatca ggatgtgcta ataacacatg
7081 ttataatgtt tcagtaatag tacctgatta tcagtgttat ttagatagag tagatacttg
7141 gttacaaggg aaaataaata tatcattatg tctaacagga ggaaaaatgt tgtacaataa
7201 agttacaaaa caattaagct attgtacaga cccattacaa atcccactga tcaattatac
7261 atttggacct aatcaaacat gtatgtggaa tacttcacaa attcaggacc ctgaaatacc
7321 aaaatgtgga tggtggaatc aaatggccta ttataacagt tgtaaatggg aagaggcaaa
7381 agtaaagttt cattgtcaaa gaacacagag tcagcctgga tcatggttta gagcaatctc
7441 gtcatggaaa caaagaaata gatgggagtg gagaccagat tttgaaagta aaaaggtgaa
7501 aatatctcta cagtgcaata gcacaaaaaa cctaaccttt gcaatgagaa gttcaggaga
7561 ttatggagaa gtaacgggag cttggataga gtttggatgt catagaaata aatcaaaact
7621 tcatgctgaa gcaaggttta gaattagatg tagatggaat gtagggagta atacctcgct
7681 cattgataca tgtggaaaca ctcaaaaagt ttcaggtgcg aatcctgtag attgtaccat
7741 gtattcaaat aaaatgtaca attgttcttt acaaaacggg tttactatga aggtagatga
7801 ccttattatg catttcaata tgaaaaaggc tgtagaaatg tataatattg ctggaaattg
7861 gtcttgtaca tctgacttgc catcgtcatg ggggtatatg aattgtaatt gtacaaatag
7921 tagtagtagt tatagtggta ctaaaatggc atgtcctagc aatcgaggca tcttaaggaa
7981 ttggtataac ccagtggcag gattacgaca atccttagaa cagtatcaag ttgtaaaaca
8041 accagattac ttagtggtcc cagaggaagt catggaatat aaacctagaa ggaaaagggc
8101 agctattcat gttatgttgg ctcttgcagc agtattatct attgccggtg cagggacggg
8161 ggctactgct atagggatgg taacacaata ccaccaagtt ctggcaaccc atcaagaagc
8221 tgtagaaaag gtgactgaag ccttaaagat aaacaactta agattagtta cattagagca
8281 tcaagtacta gtaataggat taaaagtaga agctatggaa aaatttttgt atacagcttt
8341 cgctatgcaa gaattaggat gtaatcaaaa tcaatttttc tgcaaaatcc ctcctgagtt
8401 gtggacaagg tataatatga ctataaatca aacaatatgg aatcatggaa atataacttt
8461 gggggaatgg tataaccaaa caaaagattt acaacaaaag ttttatgaaa taataatgga
8521 catagaacaa aataatgtac aagggaagaa agggatacaa caattacaaa agtgggaaga
8581 ttgggtagga tggataggaa atattccaca atatttaaag ggactattgg gaggtatctt
8641 gggaatagga ttaggagtgt tattattgat tttatgttta cctacattgg ttgattgtat
8701 aagaaattgt atccacaaga tactaggata cacagtaatt gcaatgcctg aagtagaagg
8761 agaagaaata caaccacaaa tggaattgag gagaaatggt aggcaatgtg gcatgtctga
8821 aaaagaggag gaatgatgaa gtatctcaga cttattttat aagggagata ctgtgctgag
8881 ttcttccctt tgaggaaggt atgtcatatg aatccatttc gaatcaaatc aaactaataa
8941 agtatgtatt gtaaggtaaa aggaaaagac aaagaagaag aagaaagaag aaagccttca
9001 agaggatgat gacagagtta gaagatcgct tcaggaagct atttggcacg acttctacaa
9061 cgggagacag cacagtagat tctgaagatg aacctcctaa aaaagaaaaa agggtggact
9121 gggatgagta ttggaaccct gaagaaatag aaagaatgct tatggactag ggactgttta
9181 cgaacaaatg ataaaaggaa atagctgagc atgactcata gttaaagcgc tagcagctgc
9241 ctaaccgcaa aaccacatcc tatggaaagc ttgctaatga cgtataagtt gttccattgt
9301 aagagtatat aaccagtgct ttgtgaaact tcgaggagtc tctttgttga ggacttttga
9361 gttctccctt gaggctccca cagatacaat aaatatttga gattgaaccc tgtcgagtat
9421 ctgtgtaatc ttttttacct gtgaggtctc ggaatccggg ccgagaactt cgca
//
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