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Klebsiella pneumoniae subsp. pneumoniae strain KP96_L17_12.23_ST6796_NDM5 chromosome, complete genome

发布时间：2026/4/13 8:18:44 阅读次数：4

Klebsiella pneumoniae subsp. pneumoniae strain KP96_L17_12.23_ST6796_NDM5 chromosome, complete genome
GenBank: CP138472.1
FASTA Graphics
LOCUS       CP138472                3303 bp    DNA     linear   BCT 19-NOV-2023
DEFINITION Klebsiella pneumoniae subsp. pneumoniae strain
            KP96_L17_12.23_ST6796_NDM5 chromosome, complete genome.
ACCESSION   CP138472 REGION: 1671698..1675000
VERSION     CP138472.1
DBLINK      BioProject: PRJNA1010831
            BioSample: SAMN38201183
KEYWORDS    .
SOURCE      Klebsiella pneumoniae subsp. pneumoniae
ORGANISM Klebsiella pneumoniae subsp. pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1 (bases 1 to 3303)
AUTHORS   Turton,J.F. and Turton,J.A.
TITLE     Klebsiella pneumoniae ST147 - the rise of a multiresistant and
            hypervirulent type
JOURNAL   Unpublished
REFERENCE   2 (bases 1 to 3303)
AUTHORS   Turton,J.F. and Turton,J.A.
TITLE     Direct Submission
JOURNAL   Submitted (10-NOV-2023) HCAI, Fungal, AMR, AMU & Sepsis Division,
            United Kingdom Health Security Agency, 61 Colindale Avenue, London,
            London NW9 5EQ, United Kingdom
COMMENT     The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/

            ##Genome-Assembly-Data-START##
            Assembly Date          :: 02-JUN-2023
            Assembly Method        :: Flye v. 2.9.1-b1780; Medaka v. 1.7.2
            Assembly Name          :: q20run14_BC10
            Genome Representation :: Full
            Expected Final Version :: Yes
            Genome Coverage        :: 81.0x
            Sequencing Technology :: Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##

            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 11/13/2023 12:58:50
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,908
            CDSs (total)                      :: 5,785
            Genes (coding)                    :: 5,610
            CDSs (with protein)               :: 5,610
            Genes (RNA)                       :: 123
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 175
            CDSs (without protein)            :: 175
            Pseudo Genes (ambiguous residues) :: 0 of 175
            Pseudo Genes (frameshifted)       :: 85 of 175
            Pseudo Genes (incomplete)         :: 93 of 175
            Pseudo Genes (internal stop)      :: 29 of 175
            Pseudo Genes (multiple problems) :: 26 of 175
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3303
                     /organism="Klebsiella pneumoniae subsp. pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KP96_L17_12.23_ST6796_NDM5"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /sub_species="pneumoniae"
                     /db_xref="taxon:72407"
                     /country="United Kingdom: England"
                     /collection_date="2023-03"
                     /note="genotype: ST6796"
     gene            complement(<1..2083)
                     /locus_tag="SG220_08210"
     CDS             complement(<1..2083)
                     /locus_tag="SG220_08210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004149240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="WPG45507.1"
                     /translation="MLDKININIKKTLLAFIICLVAIPLARFISPQTIIDGNLIYIAW
                     LPISVMFSVIFIFGRYAIAPLILAFAITNSFLIKLTLPQAFILLFCQLFAVFVSCAIL
                     RLLVGKRWRCGPTAKHMGARIFWGGFFAPVLLKITMYLAGQYFAFPLAITSYFGSMPL
                     IYTVIDIQSLISAALIFTTFLYYPMRMIISPRYARRFWQQECLPWLAPQYRSFTLYWF
                     IALAVILTLLCAPYQSEFIAGYLVPVIFIVYFIGISRIGHALLRISWSVSAFLLVVYN
                     KNFLQGVQSEYSLSFVLSVLISFTICLFYMADIYARSDRNKRRWRSQAEEDPLTGLPN
                     LRALESHLQSCPQQAICSLRIDNLDFLSRHYGLMMGVDCKRQIIRALQPLLGAADKVF
                     QVPGSELILVLDGPEPSSRLNHMVAVLNHKKFSWHNQPLDLEFGAAWGRDDGQGEGLY
                     QMLGQLSWLSEQAGSERRVLALDEEQDLVVDQTTEQVRLLMRVKQVLKDRALMLYAQP
                     IQNPEGEGYHEILTRMRCGDSVIMPDRFIPLIVQFNLSQRFDMLVLETLFSMLHKHPG
                     QRFSVNLLPATLMQKNSAGQIIALFQRYSVSPDTSRQNLEALRAFGCAIAIDDFGTGY
                     ANYERLKHLQADIIKIDGCFVRDILTDPLDAIMVKSIVEMAWAKQMSVVAEYVESEPQ
                     KARLLELGVNYLQGYLIGKPQPLGECRAKKSRALPGSDD"
     gene            complement(2293..2368)
                     /locus_tag="SG220_08215"
     tRNA            complement(2293..2368)
                     /locus_tag="SG220_08215"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1674030..1674032),aa:Ala,
                     seq:ggc)
     gene            complement(2410..2485)
                     /locus_tag="SG220_08220"
     tRNA            complement(2410..2485)
                     /locus_tag="SG220_08220"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1674147..1674149),aa:Ala,
                     seq:ggc)
     gene            2705..3058
                     /locus_tag="SG220_08225"
     CDS             2705..3058
                     /locus_tag="SG220_08225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="WPG45508.1"
                     /translation="MLKERMTPEEIAHLTGYSRQTINKWVRKEGWQTSPRPGVQGGKA
                     RLVHVNEQVREFIRSAQRVAETPGIYSPHDSDLESLLLTLSKELTPSEQKQLMSLLLR
                     EGITGLLLRLGIRDR"
     gene            3062..>3303
                     /locus_tag="SG220_08230"
     CDS             3062..>3303
                     /locus_tag="SG220_08230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="WPG45509.1"
                     /translation="MMKLKDKMTPAELADCLGLARQTINRWVREKQWRTEAIPGVKGG
                     RARLVVIDQPVREFLTNIPARRHLLTDNHLAESPGAYLVNEADAIWRQITETLQLMTP
                     AEQLQLRDLLAREGISGFLARLGIASPE"
ORIGIN
        1 gcagataatt cacgcccagc tccagcaagc gcgctttttg cggttcgctt tcgacatatt
       61 ccgccaccac gctcatctgt ttcgcccacg ccatctcgac aatcgatttc accatgatgg
      121 cgtccagcgg gtccgtgagg atatcgcgga cgaagcagcc gtcaatctta atgatatcgg
      181 cctgtagatg tttcagacgt tcatagttcg catagccggt gccaaagtca tcaatagcga
      241 tggcgcagcc aaacgcgcgc aacgcttcaa gattttgccg actggtgtcc ggcgagacgc
      301 tatagcgttg aaacagcgcg ataatctgcc ctgcgctgtt cttttgcatc agagttgcag
      361 gcagcaggtt gaccgagaat cgctggccgg gatgcttatg gagcatactg aacaaggtct
      421 ccagcaccag catgtcaaaa cgttggctga ggttaaactg cacaatcagc ggaatgaatc
      481 ggtcgggcat aatgacgcta tcgccacagc gcatgcgcgt gaggatctca tgataaccct
      541 ccccctccgg attctgaatc ggttgcgcat agagcatcag cgcgcgatct ttgagcactt
      601 gcttgacgcg cataaggagg cgcacctgct cggtagtttg atccaccacc agatcctgct
      661 cctcgtccag cgccagcacc cgacgttcac tgcccgcctg ttcggaaagc cagcttagct
      721 ggcccagcat ctggtaaagt ccctcaccct ggccgtcatc gcggccccag gccgcgccaa
      781 actccaaatc cagcggctga ttgtgccagc tgaacttttt gtggttgagg accgcgacca
      841 tatggttcaa gcgggacgac ggctccggcc catcaagcac gaggatcagt tcgctgcccg
      901 gtacctggaa gactttatcc gccgctccca gcagcggttg cagcgcccga ataatctgcc
      961 gtttacagtc cacccccatc atcagaccat aatgccgact gagaaagtcg agattatcaa
     1021 tacgcaggct gcagatagcc tgctgaggac agctctgtaa atggctctcc agcgcgcgca
     1081 ggttaggcaa gccggtcagc ggatcctctt ccgcctggct acgccagcgg cgtttgttgc
     1141 ggtcgctgcg ggcatagatg tcggccatat aaaacaaaca gatagtaaag gagatcagaa
     1201 ccgacagcac aaaggagagt gaatactcgc tttgcacccc ctggagaaag tttttgttat
     1261 ataccaccag caaaaaggcc gagacagacc atgaaatacg caatagcgca tggcctattc
     1321 gactgatacc gataaagtag acaataaaaa taaccggaac taaataaccg gcaataaatt
     1381 cagactgata cggcgcacac aatagcgtta atatcaccgc caacgcgata aaccaatata
     1441 gggtaaagga gcgatattgc ggtgccagcc acggtaaaca ttcctgctgc cagaaacgtc
     1501 gggcgtagcg cggactgata atcatccgca ttggataata aagaaacgtc gtaaaaatta
     1561 atgccgcact gattaaactt tggatatcta ttacagtata aatcaacggc atactaccaa
     1621 agtaactggt aatagctaat ggaaacgcaa aatattgtcc ggcgagatac atggtgattt
     1681 tcaggagcac cggcgcgaag aagccgcccc agaagatccg cgcccccata tgttttgccg
     1741 ttggaccgca gcgccagcgc ttccccacca acagtcgcag aatagcgcag gagacaaaca
     1801 cggcgaacag ttgacaaaaa agtaagataa acgcctgcgg cagcgttaat ttaatgagaa
     1861 aactattggt gatggcaaac gcgagaatta atggcgcaat tgcatagcgg ccaaagataa
     1921 aaataacaga aaacatcacg ctgattggca gccaggcaat ataaataagg ttgccgtcaa
     1981 ttatcgtttg cggtgaaata aaacgagcca gcggaatagc gactaaacaa atgataaagg
     2041 ccaatagagt ttttttgata ttaatgttaa ttttatcaag cattattgtt aattaaaact
     2101 ccagaaacct catcacgttt aatgggggaa atgttatgtt gcttatttag ggcaggcaag
     2161 gcgaattatc aggaaaaagt ctgaaattac tttcgatttt aattgctgga gattaactga
     2221 cgtaaccaga aagtgcttta catgaaaccc gctaaaaaca aaaacccccg ccgaagcgag
     2281 ggttctgaat tttggtggag ctaagcggga tcgaaccgct gacctcttgc atgccatgca
     2341 agcgctctcc cagctgagct atagccccac aggacttctt tacgaaccaa atccgctggg
     2401 tgcagaattt ggtggagcta agcgggatcg aaccgctgac ctcttgcatg ccatgcaagc
     2461 gctctcccag ctgagctata gccccgtaac gtaaagcgtg tcgtgttgac gggcggcata
     2521 atatgaattc ctcgctcagg tgtcaacggc aaaattatcc ttcccgattc aatcgctgaa
     2581 aaagcaggca acttgctgac attgcgagcc ttatcgcagt cagaagttaa acaggtcacc
     2641 ttttcacgta aaaggatgct ataacatggg cagctaattc ccatacattt actcaggaaa
     2701 tagtatgctc aaggaacgaa tgacacctga agaaattgcc catctaaccg gctacagtcg
     2761 gcaaactatc aataagtggg tgcggaaaga aggctggcaa acctctccgc gacctggcgt
     2821 ccagggcggc aaagcgcgcc tggtccatgt caatgagcaa gtcagggagt ttatccgcag
     2881 cgcccagcgc gtggcggaga cgcccggcat ctattctccc catgatagcg atctggaatc
     2941 gctgctgctg accctcagta aagaactcac ccccagcgag cagaagcagc ttatgtcatt
     3001 gttgctgcgc gaggggatca ccgggttact gcttcggtta gggatccgcg atcggtaaac
     3061 catgatgaaa ctgaaagata aaatgacgcc cgcagagctt gccgactgcc tggggctggc
     3121 cagacaaacg atcaatcgct gggttcgcga gaaacaatgg cgcaccgaag caatacccgg
     3181 cgttaaaggg gggcgagcgc gactggtggt tatcgaccaa ccggtacgcg agtttctgac
     3241 caacatccct gccagacgcc atctgcttac cgacaatcat ctcgcggaat caccaggtgc
     3301 ata
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