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Salmonella enterica subsp. enterica serovar Typhi strain R19.2839 chromosome, complete genome
GenBank: CP046429.1
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LOCUS CP046429 11001 bp DNA linear BCT 09-JUL-2021
DEFINITION Salmonella enterica subsp. enterica serovar Typhi strain R19.2839
chromosome, complete genome.
ACCESSION CP046429 REGION: 3668000..3679000
VERSION CP046429.1
DBLINK BioProject: PRJNA478278
BioSample: SAMN13219579
KEYWORDS .
SOURCE Salmonella enterica subsp. enterica serovar Typhi (Salmonella
typhi)
ORGANISM Salmonella enterica subsp. enterica serovar Typhi
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Salmonella.
REFERENCE 1 (bases 1 to 11001)
AUTHORS Chiou,C.-S., Hong,Y.-P., Wang,Y.-W. and Chen,Y.-S.
TITLE Multidrug resistant Salmonella enterica subsp. enterica serovar
Typhi strain R19.2839
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 11001)
AUTHORS Chiou,C.-S., Hong,Y.-P., Wang,Y.-W. and Chen,Y.-S.
TITLE Direct Submission
JOURNAL Submitted (28-NOV-2019) Center for Diagnostics and Vaccine
Development, Centers for Disease Control, Taiwan, No.20, Wenxin S.
3rd Rd., Nantun Dist., Taichung City 408, Taiwan
COMMENT Bacteria and source DNA available from Taichung Veterans General
Hospital.
The annotation was added by the NCBI Prokaryotic Genome Annotation
Pipeline (PGAP). Information about PGAP can be found here:
https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
##Genome-Assembly-Data-START##
Assembly Date :: 08-NOV-2019
Assembly Method :: unicycler v. v0.4.6
Assembly Name :: R19.2839
Genome Representation :: Full
Expected Final Version :: No
Genome Coverage :: 100.0x
Sequencing Technology :: Illumina MiSeq; Oxford Nanopore
##Genome-Assembly-Data-END##
##Genome-Annotation-Data-START##
Annotation Provider :: NCBI
Annotation Date :: 12/02/2019 13:25:41
Annotation Pipeline :: NCBI Prokaryotic Genome
Annotation Pipeline (PGAP)
Annotation Method :: Best-placed reference protein
set; GeneMarkS-2+
Annotation Software revision :: 4.10
Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA;
repeat_region
Genes (total) :: 4,809
CDSs (total) :: 4,698
Genes (coding) :: 4,438
CDSs (with protein) :: 4,438
Genes (RNA) :: 111
rRNAs :: 8, 7, 7 (5S, 16S, 23S)
complete rRNAs :: 8, 7, 7 (5S, 16S, 23S)
tRNAs :: 80
ncRNAs :: 9
Pseudo Genes (total) :: 260
CDSs (without protein) :: 260
Pseudo Genes (ambiguous residues) :: 0 of 260
Pseudo Genes (frameshifted) :: 135 of 260
Pseudo Genes (incomplete) :: 78 of 260
Pseudo Genes (internal stop) :: 86 of 260
Pseudo Genes (multiple problems) :: 36 of 260
CRISPR Arrays :: 1
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..11001
/organism="Salmonella enterica subsp. enterica serovar
Typhi"
/mol_type="genomic DNA"
/strain="R19.2839"
/serovar="Typhi"
/isolation_source="blood"
/host="Homo sapiens"
/sub_species="enterica"
/db_xref="taxon:90370"
/country="India:Pakistan"
/collection_date="2019"
/collected_by="Centers of Disease Control, Taiwan"
gene <1..1159
/locus_tag="GJS36_18115"
CDS <1..1159
/locus_tag="GJS36_18115"
/inference="COORDINATES: similar to AA
sequence:RefSeq:WP_000925246.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=2
/transl_table=11
/product="fimbrial protein"
/protein_id="QGT88198.1"
/translation="MLLKNTTWFAAFFLMMAIMSNCYAINTTLAVGDYASSEHDGPSG
DSVFTDNSHNFGQTIAIHKETALRQITVFNWSGIQYVMEMFCNGSGNHTYLQLTHNYI
SAGKSYNGHPLYKTSIPGFYFTIEMTFLQPAENMTSSTFWFDKTSTPITSEFTEFPSA
CSRTNVYSNLGKLMYGLKIYAYVDSDFAPTEAQLQSFTLSKNGDSDFYIDNPGSGLSN
YKMKFNLAATGLKAVWPTCSASTISGTNVSGSTVKLGSFYPKQIMEGLSPTKFQINLS
SCQYINNIEVKLASNNVGTKNTSLLTNNSTSNTKASGIGVLIEGLKSSSSAQMVLKPN
DSSSIYKDTTNNTGDGSPVGSATKSLYFQATLKPDGDNPTINPGDFKATAQFSITYP"
gene 1269..2063
/gene="panB"
/locus_tag="GJS36_18120"
CDS 1269..2063
/gene="panB"
/locus_tag="GJS36_18120"
/EC_number="2.1.2.11"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454791.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="3-methyl-2-oxobutanoate
hydroxymethyltransferase"
/protein_id="QGT88199.1"
/translation="MSKPTTIAVLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLV
GDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQAFENAA
IVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAG
QILLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDA
FGITGGHIPKFAKNFLAEAGDMRAAVRQYMAEVESGVYPGEEHSFH"
gene 2189..3043
/gene="panC"
/locus_tag="GJS36_18125"
CDS 2189..3043
/gene="panC"
/locus_tag="GJS36_18125"
/EC_number="6.3.2.1"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454790.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="pantoate--beta-alanine ligase"
/protein_id="QGT88200.1"
/translation="MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEA
KARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQG
LEGQTYVDVPGLSTMLEGTSRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
KMVADMGYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAG
NRELQEIIAIAEQELNEKGFRADDIQIRDADTLLELTETSKRAVILAAAWLGQARLID
NQSVTLAQ"
gene 3138..3518
/gene="panD"
/locus_tag="GJS36_18130"
CDS 3138..3518
/gene="panD"
/locus_tag="GJS36_18130"
/EC_number="4.1.1.11"
/inference="COORDINATES: similar to AA
sequence:RefSeq:WP_005124704.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="aspartate 1-decarboxylase"
/protein_id="QGT88201.1"
/translation="MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAI
DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWR
PKVAYFEGDNEMKRTAKAIPVQVA"
gene complement(3525..4754)
/locus_tag="GJS36_18135"
CDS complement(3525..4754)
/locus_tag="GJS36_18135"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_459184.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="polysaccharide deacetylase family protein"
/protein_id="QGT88202.1"
/translation="MVMRVVLILLFFFAGNVLAALPARYMQTTKDAAIWSQIGDKMVT
VGNIRAGQILSVTPVAVDYYAFKFGFGVGFIDKGHLGPVQGKQKVEDGLGDLNKPLSN
QNLVTWKDTPVYNAPDISSAPFGVLVDNLRYPIISKLKGRLHQTWNQIRIGDRLAYVN
AMDAQEDNGIPILTYHHILRDEENTRFRHTSTTTSVRAFSNQMTWLRDRGYATLTMYQ
LEDYIYNRANFPARAVAITFDDGLKSVSRYAYPVLKQYDMKATAFIISSRIKRHPQKW
NPRSLQFMSVSELRKISDVFDFQSHTHFLHRVDGHRRPILYSRSYHNILFDFERSRRA
LTQFTPHVFYLSYPFGGYNATAIKAAKDAGFHLAVTTVRGKVKPGDNPMLLKRLYILR
TDSLETMSRLIVNQPQG"
gene complement(4816..5256)
/locus_tag="GJS36_18140"
CDS complement(4816..5256)
/locus_tag="GJS36_18140"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454787.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="PTS sugar transporter subunit IIA"
/protein_id="QGT88203.1"
/translation="MLGWVITCHDDRAQDMLDRLERKNGPLAQCRAVNFWRGLSSNML
SRMMCDALHATDSGEGVIFLTDISGAAPYRVASLMSHKHPQCEVISGISYSLIEEMIP
LRESMSSSAFRDQIVALGAPDVTSLWHQQQKNPPFVLLHDLYEF"
gene complement(5361..6131)
/locus_tag="GJS36_18145"
CDS complement(5361..6131)
/locus_tag="GJS36_18145"
/inference="COORDINATES: similar to AA
sequence:RefSeq:WP_001747261.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="ABC transporter permease"
/protein_id="QGT88204.1"
/translation="MMQLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
LIGSRIGEMHGFSYMQFIVPGLIMMAVITNSYANVASSFFSAKFQRNIEELLVAPVPT
HVIIAGFVGGGVARGLCVGILVTAISLFFVPFQVHSWVFVALTLILTAILFSLAGLLN
AVFAKTFDDISLIPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
LGIHDVPLVTTFGVLVIFIATFYLLCWSLIQRGRGLRS"
gene complement(6128..7054)
/locus_tag="GJS36_18150"
CDS complement(6128..7054)
/locus_tag="GJS36_18150"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454785.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="ATP-binding cassette domain-containing protein"
/protein_id="QGT88205.1"
/translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
STTIGIISSLVNKTSGRVNVFGYDLEKDVVNAKRQLGLVSQEFNFNPFETVQQIVVNQ
AGYYGVEHKEAVLRSEKYLKQLDLWEKRHERARMLSGGMKRRLMIARALMHEPKLLIL
DEPTAGVDIELRRSMWGFLKDLNAKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
SMKNLLSKLKSETFILDLAPKSPLPKLTGYQYRLVDTSTLEVEVLREQGVNSVFSQLS
EQGVQVLSMRNKANRLEELFVSLVHEKQGDRA"
gene 7163..7825
/locus_tag="GJS36_18155"
CDS 7163..7825
/locus_tag="GJS36_18155"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454784.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="carbonate dehydratase"
/protein_id="QGT88206.1"
/translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDALEVEHIIICGHSGCG
GIKAAVENPELGLINNWLLHIRDIWLKHSSLLGKMPEEQRLDALYELNVMEQVYNLGH
STIMQSAWKRGQNVTIHGWAYSINDGLLRDLDVTATNRETLENGYHKGISALSLKYIP
HQ"
gene complement(7883..8419)
/locus_tag="GJS36_18160"
CDS complement(7883..8419)
/locus_tag="GJS36_18160"
/EC_number="2.4.2.8"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454783.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="hypoxanthine phosphoribosyltransferase"
/protein_id="QGT88207.1"
/translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSDSEMVLVGLLRG
SFMFMADLCREVQVPHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
DSGNTLSKVREILGLREPKSLAICTLLDKPSRREVDVPVEFVGFSIPDEFVVGYGIDY
AQRYRHLPYVGKVVLLDE"
gene 8625..>11001
/locus_tag="GJS36_18165"
CDS 8625..>11001
/locus_tag="GJS36_18165"
/EC_number="1.1.-.-"
/inference="COORDINATES: similar to AA
sequence:RefSeq:NP_454782.1"
/note="Derived by automated computational analysis using
gene prediction method: Protein Homology."
/codon_start=1
/transl_table=11
/product="membrane-bound PQQ-dependent dehydrogenase,
glucose/quinate/shikimate family"
/protein_id="QGT88208.1"
/translation="MAENNARSPRLLVTLTALFAALCGLYLLIGGVWLVAIGGSWYYP
IAGLVMLVVAGLLWRSKRAALWLYAALLLATMIWGVWEVGFDFWALTPRSDILVFFGI
WLILPFVWHRLVVPSSGAVAALVVALLISGGILTWAGFNDPQEINGTLRADATPAATS
SSIADEDWPAYGRNQEGQRYSPLKQITADNVHQLKEAWVFRTGDLKQPNDPGEITNEV
TPIKVGDTLYLCTAHQRLFALDAASGKEKWHFDPQLKTDSSFQHVTCRGVSYHEAKAD
TASPEVIADCPSRIILPVNDGRLFAVNAETGKLCETFANKGVLNLQTNMPDTTPGLYE
PTSPPIITDKTIVIAGSVTDNFSTRETSGVIRGFDVNSGKLLWAFDPGAKDPNTIPAD
EHAFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
GKLAWSYQTVHHDLWDMDLPAQPTLADITVDGTTVPVIYAPAKTGNIFVLDRRNGELV
VPAPEKPVPQGAAKGDYVAKTQPFSDLTFRPKKDLSGADMWGATMFDQLVCRVMFHQL
RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPDRQVAIANPMALPFVSKLIPRGPGN
PMEPPKDAKGTGTEAGIQPQYGVPFGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEI
VWKKRIGTPRDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDAK"
ORIGIN
1 aacatggttt gccgcctttt tcctgatgat ggctatcatg tccaactgtt atgccataaa
61 tactaccctg gccgttggcg actacgcctc cagtgaacat gatggcccaa gcggggattc
121 ggtattcact gataacagcc acaattttgg gcagaccatc gcgattcata aggaaacggc
181 gctgcgccag attaccgttt ttaactggtc cggcatccag tacgttatgg agatgttctg
241 taacggcagc ggcaaccaca cctaccttca actgacccat aattatatct ctgctggcaa
301 aagctataat ggacatccgc tgtataaaac ctcaattccc ggtttttatt tcaccattga
361 gatgaccttc cttcagccag cagagaatat gacctcaagc accttctggt ttgataagac
421 ctcaacgccg atcaccagcg agttcacgga atttccgtca gcctgctcca gaacaaatgt
481 ttatagcaac cttggcaaat taatgtatgg cctgaaaatc tatgcctatg tcgactctga
541 cttcgcgccg acggaagccc agcttcaaag ctttacgctg tctaaaaacg gcgactccga
601 tttctacatt gataacccgg gcagcggatt atcaaactat aaaatgaagt ttaacctcgc
661 cgccacagga cttaaggccg tctggccaac ctgctcggcc agcaccatta gcggcaccaa
721 tgtttcggga tcaacggtta agctgggtag cttttatcca aagcagatta tggaagggct
781 gtcgccgacc aagttccaga tcaatctctc ctcctgccag tacatcaata atattgaagt
841 taaattggcc agtaataatg tcgggacgaa aaacacctcg ctactaacca acaattcaac
901 cagcaacacg aaagccagcg gcattggcgt tttaattgaa ggtttgaaaa gtagttcgag
961 cgcccagatg gtactcaaac ctaacgactc aagctcaatt tataaagata ccaccaataa
1021 caccggagac ggcagcccgg taggaagcgc gacaaaatcg ttgtatttcc aggcaacctt
1081 aaagcccgat ggtgacaatc caacaatcaa tccaggtgat ttcaaagcca ccgctcaatt
1141 ttcaatcacc tatccgtaaa atcctataac gaaccgcaac gcaatttgcc cagaaaaggc
1201 taacgcttgc ggttctcttc ccctacaatg cggccattct attcatcaat attatggccg
1261 gagaggttat gagcaaaccc actactatcg ctgtgctgca gaaatgcaaa caagagaaaa
1321 agcgcttcgc caccattacc gcgtacgatt acagcttcgc caaactcttc gccgatgaag
1381 gcatcaatgt gatgctggtt ggcgactcgc tgggcatgac aattcagggg cacgactcca
1441 ccctgcctgt caccgtggaa gatatcgcct accacacccg cgcggtacgc cgcggcgcgc
1501 cgaactgcct gctgctctcc gacctgccgt ttatggctta cgccacgccg gaacaggcgt
1561 ttgaaaacgc ggctatcgtg atgcgtgcgg gggccaacat ggtcaaaatc gaaggcggcg
1621 catggttggt tgatacggtg aaaatgctca ccgaacgcgc cgtgccggtg tgtggccatc
1681 tgggattaac tccccagtcg gtgaatatct tcggcggcta taaaattcag ggccgcggcg
1741 atgccgggca gatactgctg gatgatgcgc tggccttaga agcagcgggc gctcaactgc
1801 tggtgctgga gtgcgtgccg gttgaactgg cgaagcgcgt cacggaagcg ctgtcgattc
1861 cggtgatcgg catcggcgcg ggcaacgtca ccgacggtca gatcctggtg atgcacgatg
1921 cgtttggcat caccggcggt catattccaa aattcgcgaa aaatttcctt gccgaggcgg
1981 gcgacatgcg cgccgccgta cggcagtata tggcagaagt ggagtccggc gtttatccgg
2041 gcgaagaaca cagctttcac taatttttct gaccgtgccg gatagcgacg cgacgcgtct
2101 tatccggcct acagatcctc aacggatgta ggcctgataa gcgcagcgcc atcgggctgg
2161 atcatcaagc aactcaagga gtcttgttgt gttaatcatt gaaaccctgc cgctgctgcg
2221 ccagcatatt cgccgtctgc gtcaggaagg caaacgcgtc gcactggttc ccactatggg
2281 caacctgcac gacggccata tgaagctggt cgatgaggca aaagcccggg ccgatgtggt
2341 catcgtcagc attttcgtca acccgatgca atttgatcgg ccggacgatc tggtgcgcta
2401 tccgcgcacg ttgcaggaag attgtgaaaa gctgaacaaa cgcaaagtcg attatgtctt
2461 tgccccagcc gttgaggaaa tctaccctca ggggctggaa ggacagacat acgttgacgt
2521 tcccggcctc tctaccatgc tggaaggcac cagccgtccg ggccacttcc gcggcgtctc
2581 gaccatcgtc agcaagctgt tcaaccttat ccagccggat atcgcctgct ttggcgagaa
2641 agatttccag cagctggcgc tgatccgcaa aatggtggcg gatatgggtt atgacattga
2701 gatcgtcggt gtgccgatta ttcgcgctaa agacggtctg gcgctcagct cacgtaacgc
2761 ttatctgact gcagagcagc gcaaaattgc gccgggtcta tacaacgtga tgaatagcat
2821 cgctgaaaaa ctgattgcgg gtaatcgtga gctgcaagag attattgcca ttgccgagca
2881 ggaactgaat gaaaaaggct tccgtgccga cgacattcaa atccgtgatg ccgacacgct
2941 gctggagctg acggaaacca gcaaacgcgc agtgattctg gctgccgcct ggctgggaca
3001 ggcgcgtctg atcgataatc aaagcgttac attagcccag tagacagggg ttaaaaatcg
3061 ggcaatactg cctgagaatt tccaaagcag gctacaagcg cctgcttagc caagataaac
3121 gacagggtat agaagttatg attcgcacca tgctgcaagg caagctccac cgcgtaaaag
3181 tcacgcaggc ggacctgcac tacgaaggct cctgcgccat tgaccaggat ttccttgatg
3241 cctccggtat tctggaaaac gaagcgattg atatctggaa cgtgaccaat gggaaacgtt
3301 tctcaaccta tgcgattgcg gctgaacgcg gctccagaat catctcggtg aacggtgcgg
3361 cggcgcactg cgctgaagtt ggcgacattg tgattatcgc cagcttcgtc accatgtctg
3421 atgaagaagc gcgtacatgg cgtccgaaag tggcctactt tgaaggcgac aacgaaatga
3481 agcgcaccgc gaaagccatt ccggttcagg ttgcctgata gtccttaccc ctgcggctga
3541 ttgactatca gccgcgacat cgtttccagc gaatccgtgc gtaaaatata cagccttttg
3601 agcagcatcg gattatctcc cggcttcacc ttccctctca ccgtggtgac cgccagatgg
3661 aaaccggcgt cttttgctgc tttgatcgcg gtcgcgttat agccgccaaa gggataagaa
3721 agataaaata cgtgcggagt aaactgtgtg agcgcccgcc gcgaacgttc aaaatcaaac
3781 agaatattat ggtaactgcg gctatataaa atcgggcggc gatgcccgtc tacccggtgt
3841 aaaaaatggg tatgcgactg aaaatcaaaa acatcgctta tcttgcgcaa ttcggacacg
3901 ctcataaatt gcagcgacct gggattccat ttttgcggat ggcgcttaat acgcgatgag
3961 ataataaatg ccgtcgcttt catatcgtac tgctttaata ccggatatgc atagcgactc
4021 accgatttaa ggccatcatc aaaggtgata gccaccgcgc gcgccgggaa attagcgcgg
4081 ttatagatgt aatcctccag ttggtacatc gtcaacgtgg catagccgcg atcgcgaagc
4141 caggtcattt ggttgctgaa tgcccgaacc gaagtcgtgg tggaggtatg gcgaaaacgg
4201 gtattctctt catcacgtaa aatgtgatga taggtcaaaa tcggaatgcc gttgtcttcc
4261 tgcgcatcca tggcgttgac ataagccagc ctgtcgccaa tacggatctg attccaggtt
4321 tgatgtagcc ggcctttcag cttgctaata atggggtaac gcaaattatc caccaatacg
4381 ccaaacgggg cgctactgat gtccggcgcg ttatacaccg gcgtgtcctt ccaggtcacc
4441 agattctgat tgctgagcgg cttgttaaga tcgcccagcc catcttccac tttttgtttt
4501 ccctgcacgg gtcccagatg gcctttatcg ataaacccca caccgaagcc aaatttaaag
4561 gcataataat caaccgcaac aggcgttacg gaaagaattt gtccggcgcg gatattccct
4621 acggtcacca ttttgtcgcc aatctgcgac cagatggcgg catctttcgt cgtttgcata
4681 taacgagcgg gcaaggcagc caacacatta ccggcgaaaa agaacagcaa gataagaaca
4741 acacgcataa ccatatatca taaccgaggc gaaaaaacgc cgttattgta gcaaaagcgt
4801 cgtcaatggt attgatcaaa actcatacaa atcatgcagc aatacaaaag gcggattttt
4861 ctgctgctga tgccagagac tggtgacatc cggcgcgcca agcgcgacaa tctggtcacg
4921 aaatgctgaa ctgctcatcg actctcgcaa aggaatcatt tcctctatca atgaatagct
4981 aatgcctgaa ataacttcac attgaggatg tttatggctc atcagcgacg ctacacgata
5041 aggcgccgcg ccggaaatgt cggttaaaaa tatcacgcct tcaccggaat cggtggcatg
5101 gagggcatca cacatcatgc ggctcagcat gtttgagctc agaccgcgcc aaaaattgac
5161 cgcccggcat tgcgccagcg gaccattttt tctctccagg cgatcaagca tatcctgtgc
5221 acgatcgtca tggcaggtaa tcacccaacc taacataacc tacctcctta gcaggcaagt
5281 agtttatcag ggtgatcaat cgggaatgat gacagccgtc aaaagtctcc tcttccctcc
5341 aggagaagag gagaatcgta tcagctacgc aaaccgcgtc cgcgctggat cagcgaccaa
5401 cacagcagat agaaagtagc gataaagatc accagtacgc caaacgttgt caccagcggc
5461 acatcatgga tacccagaaa accataacgg aaaccgctga tcatgtagac gatcgggttc
5521 aggtgcgaca acccttgcca gaacggcggc agcagcgtca gcgagtaaaa taccccgccg
5581 aggtaggtca gcggcgtcag cacaaaggtc gggatcagac tgatatcgtc aaaggttttg
5641 gcaaacacgg cgttcagcag tccggccagc gagaacagaa tcgcggtcag aatcagcgtt
5701 agcgcgacaa atacccagga atgcacctgg aaaggcacga aaaagagcga aatcgccgtc
5761 accagaatcc ccacgcacag cccgcgcgcc acgccgccgc cgacaaatcc ggcgatgatc
5821 acgtgcgttg gcaccggcgc gaccagcagt tcctcaatat tgcgctgaaa cttggcgcta
5881 aagaacgagg aggccacatt ggcgtaggag ttagtaatga ccgccatcat aatcaggccc
5941 ggcacaataa attgcatata gctaaagcca tgcatttcgc cgatgcgcga accgatcagg
6001 ttaccgaaaa taataaaata gagcgtcatg gtgatgacag gcggcaccag cgtttgcacc
6061 cagatccgca taaagcggtg gatctctttc gcccagatgc ttttaagggc aacccagtaa
6121 agctgcatca tgcgcgatct ccttgttttt catgcaccag cgacacaaac agttcttcca
6181 gacggttggc tttattacgc atacttaata cctgaacccc ctgctcgctc agttggctaa
6241 agacgctgtt aaccccctgc tcgcgtaaca cttccacctc cagagtcgag gtatccacca
6301 gacgatattg ataacccgta agcttaggta gcgggctttt gggcgctaaa tccagaataa
6361 atgtctccga tttcagcttt gaaagcagat ttttcatgga agtattttcc accagctcgc
6421 cgtgctgaat aataccgata ttgcggcaca gcatttccgc ctcttccaga tagtgggtgg
6481 tgagaataat ggtggtgcct ttggcgttta agtctttcag gaacccccac attgagcgac
6541 gtaattcgat atcgacgccc gccgtcggct cgtcgagaat caatagttta ggctcatgca
6601 tcaatgcgcg ggcgatcatc aggcggcgtt tcatcccacc ggacagcatc cgcgcgcgtt
6661 catgacgttt ttcccacaga tcgagctgtt ttaaatactt ttcgctacgt aaaaccgcct
6721 ctttatgctc cacgccgtaa taacccgcct gattcactac gatctgttgc accgtttcaa
6781 acgggttaaa gttaaactcc tgtgacacca gtccaagctg tcgcttggcg ttaaccacgt
6841 ctttttccag gtcgtaacca aaaacgttaa cgcgcccgga cgttttatta accaatgagc
6901 tgataatacc gatggtggtc gatttccctg ctccatttgg ccccagaagc gcgtaaaaat
6961 cccccgcttc gacctgcaaa tctatgccgc gcagcgcctg aacgccgccg ggataggttt
7021 ttttaagttg ttgaagttcc agcgcaatgg tcataaattc tcacttactt tacgttctta
7081 cactttatat atggtttaaa taattacgga gttgccctat attagcccaa cgcacttatt
7141 tggttacagg tcgttaactt ccatgaaaga catagataca ctcatcagca acaatgcact
7201 atggtcaaaa atgctggtgg aagaggaccc cggatttttt gagaaactgg cgcaagcgca
7261 aaaaccgcgc tttctatgga ttggatgttc cgacagccgc gttcccgcag agcgtttaac
7321 cgggcttgaa ccgggcgaat tgtttgttca ccgtaatgtg gctaacctgg ttattcacac
7381 cgatctgaac tgtctctccg tggttcagta tgcggtagat gctctggaag ttgagcatat
7441 tatcatttgc ggccactccg gttgcggcgg tatcaaggct gcggtagaaa accctgagct
7501 gggcttgatt aataactggc tgctgcatat ccgcgacatc tggcttaaac atagctcgct
7561 gttgggaaaa atgcccgaag agcaacgtct ggacgcgctc tatgaattga acgtcatgga
7621 gcaggtctat aacctggggc attccaccat tatgcagtca gcgtggaaac gcgggcagaa
7681 tgtgaccatt cacggctggg cgtacagtat caatgatggc ctgctgcgcg atcttgacgt
7741 caccgccacc aacagagaaa cgctggagaa cggctatcat aagggtatct ccgccctaag
7801 tctgaaatac attccccacc aataagccat tagctatagg ccggataagt cgctttagcg
7861 acgccatccg gcatttctgc gcttactcgt ccagcagcac cactttacca acatacggta
7921 gatggcgata acgctgggcg tagtcgatac cgtaaccgac tacaaattcg tccggaatcg
7981 aaaagccaac gaactcaacc ggcacgtcca cttctcggcg agacggctta tccagcagcg
8041 tacaaatcgc cagcgatttc ggctcgcgca ggcccaggat ttcacggacc ttcgacagcg
8101 tattaccgga atcaataatg tcttcgacaa tcagcacgtc tttaccacga atatcctcat
8161 ccagatcttt gaggattttc acgtcgcggg tggtggacat accgctacca taactggagg
8221 cggtcataaa atcgacttca tgaggaacct gaacttcacg gcacaggtcc gccataaaca
8281 taaatgagcc acgcaacaga cctaccagca ccatttcact gtcgctgtct ttataacgtt
8341 cggtaatctg acgacccagc tcggcaatac gtgctttgat ctccgcttcg gggatcatga
8401 cttcaacagt atgtttcata tttataacca tatgatttaa aaacaaatca ctcaatgccg
8461 gtgactaata acgccgcatt gacgcgcaag gcacgcagta taacagcaaa cgtattcatt
8521 cgcggcattt gataagaaag ctcattttgt gatgacgatc acacatgtta attcctatgc
8581 ttaattgcta ctaaaaaatt aacaatttgg gatggtgtct ttttatggca gaaaataacg
8641 cacgatcgcc acgattactc gtgacgctga cggccctctt tgcagcactt tgcgggctgt
8701 atcttcttat cggaggtgtc tggctggttg ctattggcgg ttcctggtac taccccatcg
8761 cgggcctcgt gatgctggtt gtggccggat tgctatggcg cagtaaacgt gccgcactgt
8821 ggctgtatgc cgccctgctg ctggcgacaa tgatttgggg cgtgtgggaa gtcgggttcg
8881 acttctgggc actcacgccg cgtagcgata tcctggtgtt tttcggcatc tggctaatat
8941 tgccgtttgt ctggcatcgg ctggtggttc cttccagcgg cgcagtggcg gcgctggtcg
9001 tggcgctgct gattagcggc ggcattctga cctgggctgg cttcaacgac ccgcaggaga
9061 tcaacggtac gcttcgcgcc gacgccacgc ccgccgcaac aagttcgtcg atcgccgacg
9121 aagactggcc ggcctatgga cgtaatcagg aaggccaacg ctattcgccg ctgaaacaga
9181 tcactgcgga taacgttcac caactgaaag aagcgtgggt cttccgcacc ggcgatctga
9241 aacaacccaa cgatccgggt gaaatcacca acgaagtgac cccgataaaa gtcggtgata
9301 cgctttatct gtgtacagct caccagcgtc tgttcgcgct ggacgccgcc agcggtaaag
9361 agaagtggca ttttgatcct cagttgaaga ccgattcgtc tttccagcat gtgacctgcc
9421 gcggcgtctc ttatcatgag gccaaagcgg ataccgcctc gccggaggtc atcgccgact
9481 gtccgagccg cattatcctc ccggtcaacg acggtcgcct tttcgcggtg aatgccgaaa
9541 ccggcaagct gtgtgaaacc ttcgccaaca aaggcgtcct gaatctgcaa accaatatgc
9601 cggataccac gccgggactg tatgaaccga cgtcgccgcc gattatcacc gataaaacaa
9661 ttgtcattgc cggttcggtc acggataact tctctactcg cgaaacgtcc ggcgttatcc
9721 gtggttttga tgttaatagc ggtaaactac tgtgggcctt cgatcctggg gcgaaagatc
9781 cgaacacgat tccagccgat gagcacgctt ttacctttaa ctcgccgaac tcctgggccc
9841 ctgccgccta tgatgcgaaa ctggatctgg tctatctgcc gatgggcgtg accacgccgg
9901 atatctgggg cggtaaccgc acgccggagc aggaacgtta tgccagctcc atcctggcgc
9961 tgaatgccac caccgggaaa ctggcctgga gttatcagac cgtccatcac gatctgtggg
10021 atatggacct gccggcacag ccgacgctgg cggatattac cgttgacggt actaccgttc
10081 cggttatcta tgcaccagcg aaaaccggta atatctttgt gctggacaga cgtaatggcg
10141 agctggtcgt gcccgctccg gaaaaaccgg tcccgcaggg cgcggcaaaa ggcgattatg
10201 tcgccaaaac tcagccgttc tctgatttaa ccttccgccc gaaaaaagat ctctccggcg
10261 cggatatgtg gggcgcgacc atgttcgacc aactggtgtg ccgcgttatg ttccaccagt
10321 tgcgctatga aggtatcttc accccgccat ccgagcaggg gacattggta ttccctggca
10381 acctggggat gtttgaatgg ggcggtattt ccgtcgatcc agaccgtcag gtcgctatcg
10441 ctaacccgat ggcgctgccg tttgtctcga agctgatccc acgcggcccg ggtaatccaa
10501 tggaaccgcc gaaagacgcg aaaggtaccg gtacagaagc gggtattcag ccgcagtacg
10561 gcgtaccgtt cggcgtcacg ctgaatccgt tcctttcgcc gtttggtttg ccgtgtaaac
10621 aaccggcctg gggctacatt tccgcgttgg atctgaagac caatgaaatc gtgtggaaga
10681 aacgtatagg gacgccgcgc gacagtatgc cgttcccgat gccggttccg gtgccgttca
10741 acatggggat gcccatgctg ggcgggccaa tctcaaccgc cggtaacgtg ctgttcattg
10801 ccgcgaccgc cgacaactac ctgcgcgctt ataacatgag caacggggaa aaactgtggc
10861 agggacgttt acccgccgga ggccaggcaa cgccgatgac ctatgaggta aacggtaagc
10921 agtacgtggt catttctgcc ggaggccacg gttcgtttgg tacgaagatg ggcgactata
10981 tcgtggccta tgctttgcct g
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