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Human papillomavirus type 52 genomic DNA
GenBank: X74481.1
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LOCUS X74481 7942 bp DNA linear VRL 18-APR-2005
DEFINITION Human papillomavirus type 52 genomic DNA.
ACCESSION X74481
VERSION X74481.1
KEYWORDS E1 gene; E2 gene; E4 gene; E6 gene; E7 gene; early protein; L1
gene; L2 gene; late protein.
SOURCE human papillomavirus 52
ORGANISM human papillomavirus 52
Viruses; Monodnaviria; Shotokuvirae; Cossaviricota;
Papovaviricetes; Zurhausenvirales; Papillomaviridae;
Firstpapillomavirinae; Alphapapillomavirus.
REFERENCE 1 (bases 1 to 7942)
AUTHORS Delius,H. and Hofmann,B.
TITLE Primer-directed sequencing of human papillomavirus types
JOURNAL Curr. Top. Microbiol. Immunol. 186, 13-31 (1994)
PUBMED 8205838
REFERENCE 2 (bases 1 to 7942)
AUTHORS Delius,H.
TITLE Direct Submission
JOURNAL Submitted (06-AUG-1993) H. Delius, Deutsches
Krebsforschungszentrum, Abteilung ATV, Im Neuenheimer Feld 506, W
6900 Heidelberg, FRG
FEATURES Location/Qualifiers
source 1..7942
/organism="human papillomavirus 52"
/mol_type="genomic DNA"
/db_xref="taxon:10618"
/clone="insert in EcoRI site of pUC19"
gene 102..548
/gene="E6"
CDS 102..548
/gene="E6"
/codon_start=1
/product="early protein"
/protein_id="CAA52585.1"
/db_xref="GOA:P36814"
/db_xref="InterPro:IPR001334"
/db_xref="UniProtKB/Swiss-Prot:P36814"
/translation="MFEDPATRPRTLHELCEVLEESVHEIRLQCVQCKKELQRREVYK
FLFTDLRIVYRDNNPYGVCIMCLRFLSKISEYRHYQYSLYGKTLEERVKKPLSEITIR
CIICQTPLCPEEKERHVNANKRFHNIMGRWTGRCSECWRPRPVTQV"
gene 553..852
/gene="E7"
CDS 553..852
/gene="E7"
/codon_start=1
/product="early protein"
/protein_id="CAA52586.1"
/db_xref="GOA:P36831"
/db_xref="InterPro:IPR000148"
/db_xref="UniProtKB/Swiss-Prot:P36831"
/translation="MRGDKATIKDYILDLQPETTDLHCYEQLGDSSDEEDTDGVDRPD
GQAEQATSNYYIVTYCHSCDSTLRLCIHSTATDLRTLQQMLLGTLQVVCPGCARL"
gene 864..2807
/gene="E1"
CDS 864..2807
/gene="E1"
/codon_start=1
/product="early protein"
/protein_id="CAA52587.1"
/db_xref="GOA:P36730"
/db_xref="InterPro:IPR001177"
/db_xref="InterPro:IPR014000"
/db_xref="InterPro:IPR014015"
/db_xref="InterPro:IPR016393"
/db_xref="UniProtKB/Swiss-Prot:P36730"
/translation="MEDPEGTEGEREGCTGWFEVEAIIEKQTGDNISEDEDENAYDSG
TDLIDFIDDSNINNEQAEHEAARALFNAQEGEDDLHAVSAVKRKFTSSPESAGQDGVE
KHGSPRAKHICVNTECVLPKRKPCHVEDSGYGNSEVEAQQMADQVDGQNGDWQSNSSQ
SSGVGASNSDVSCTSIEDNEENSNRTLKSIQNIMCENSIKTTVLFKFKETYGVSFMEL
VRPFKSNRSSCTDWCIIGMGVTPSVAEGLKVLIQPYSIYAHLQCLTCDRGVLILLLIR
FKCGKNRLTVSKLMSQLLNIPETHMVIEPPKLRSATCALYWYRTGLSNISEVYGTTPE
WIEQQTVLQHSFDNSIFDFGEMVQWAYDHDITDDSDIAYKYAQLADVNSNAAAFLKSN
SQAKIVKDCATMCRHYKRAERKHMNIGQWIQYRCDRIDDGGDWRPIVRFLRYQDIEFT
AFLDAFKKFLKGIPKKNCLVLYGPANTGKSYFGMSLIRFLSGCVISYVNSKSHFWLQP
LTDAKVGMIDDVTPICWTYIDDYMRNALDGNDISVDVKHRALVQIKCPPLILTTNTNA
GTDPRWPYLHSRLVVFHFKNPFPFDENGNPIYEINNENWKSFFSRTWCKLDLIQEEDK
ENDGVDTGTFKCSAGKNTRSIRS"
gene 2743..3849
/gene="E2"
CDS 2743..3849
/gene="E2"
/codon_start=1
/product="early protein"
/protein_id="CAA52588.1"
/db_xref="GOA:P36796"
/db_xref="InterPro:IPR000427"
/db_xref="InterPro:IPR001866"
/db_xref="InterPro:IPR009021"
/db_xref="InterPro:IPR012677"
/db_xref="UniProtKB/Swiss-Prot:P36796"
/translation="MESIPARLNAVQEKILDLYEADSNDLNAQIEHWKLTRMECVLFY
KAKELGITHIGHQVVPPMAVSKAKACQAIELQLALEALNKTQYSTDGWTLQQTSLEMW
RAEPQKYFKKHGYTITVQYDNDKNNTMDYTNWKEIYLLGECECTIVEGQVDYYGLYYW
CDGEKIYFVKFSNDAKQYCVTGVWEVHVGGQVIVCPASVSSNEVSTTETAVHLCTETS
KTSAVSVGAKDTHLQPPQKRRRPDVTDSRNTKYPNNLLRGQQSVDSTTRGLVTATECT
NKGRVAHTTCTAPIIHLKGDPNSLKCLRYRVKTHKSLYVQISSTWHWTSNECTNNKLG
IVTITYSDETQRQQFLKTVKIPNTVQVIQGVMSL"
gene 4262..5662
/gene="L2"
CDS 4262..5662
/gene="L2"
/codon_start=1
/product="late protein"
/protein_id="CAA52589.1"
/db_xref="GOA:P36763"
/db_xref="InterPro:IPR000784"
/db_xref="UniProtKB/Swiss-Prot:P36763"
/translation="MRYRRSTRHKRASATQLYQTCKASGTCPPDVIPKVEGTTIADQL
LKYGSLGVFFGGLGIGTGAGSGGRAGYVPLSTRPPTSSITTSTIRPPVTVEPIGPLEP
SIVSMIEETTFIESGAPAPSIPSATGFDVTTSANNTPAIINVTSIGESSVQSVSTHLN
PTFTEPSIIQPPAPAEASGHVLFSSPTISTHTYEEIPMDTFVTSTDSSSVTSSTPIPG
SRPTTRLGLYSRATQQVKVVDPAFMSSPQKLVTYNNPVFEGVDTDETIIFDRSQLLPA
PDPDFLDIIALHRPALTSRRGTVRFSRLGNKATLRTRSGKQIGARVHYYHDISPIQPA
EVQEDIELQPLLPQSVSPYTINDGLYDVYADSLQQPTFHLPSTLSTHNNTFTVPINSG
IDFVYQPTMSIESGPDIPLPSLPTHTPFVPIAPTAPSTSIIVDGTDFILHPSYFLLRR
RRKRFPYFFTDVRVAA"
gene 5565..7154
/gene="L1"
CDS 5565..7154
/gene="L1"
/codon_start=1
/product="late protein"
/protein_id="CAA52590.1"
/db_xref="GOA:Q05138"
/db_xref="InterPro:IPR002210"
/db_xref="InterPro:IPR011222"
/db_xref="UniProtKB/Swiss-Prot:Q05138"
/translation="MVQILFYILVIFYYVAGVNVFHIFLQMSVWRPSEATVYLPPVPV
SKVVSTDEYVSRTSIYYYAGSSRLLTVGHPYFSIKNTSSGNGKKVLVPKVSGLQYRVF
RIKLPDPNKFGFPDTSFYNPETQRLVWACTGLEIGRGQPLGVGISGHPLLNKFDDTET
SNKYAGKPGIDNRECLSMDYKQTQLCILGCKPPIGEHWGKGTPCNNNSGNPGDCPPLQ
LINSVIQDGDMVDTGFGCMDFNTLQASKSDVPIDICSSVCKYPDYLQMASEPYGDSLF
FFLRREQMFVRHFFNRAGTLGDPVPGDLYIQGSNSGNTATVQSSAFFPTPSGSMVTSE
SQLFNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMTLCAEVKKESTYKNENFKE
YLRHGEEFDLQFIFQLCKITLTADVMTYIHKMDATILEDWQFGLTPPPSASLEDTYRF
VTSTAITCQKNTPPKGKEDPLKDYMFWEVDLKEKFSADLDQFPLGRKFLLQAGLQARP
KLKRPASSAPRTSTKKKKVKR"
ORIGIN
1 taaattataa tcttatacta gtaaaaaata gggtgtaacc gaaaacggtc agaccgaaac
61 cggtgtatat atatagaaca cagtgtagct aacgcacggc catgtttgag gatccagcaa
121 cacgaccccg gaccctgcac gaattgtgtg aggtgctgga agaatcggtg catgaaataa
181 ggctgcagtg tgtgcagtgc aaaaaagagc tacaacgaag agaggtatac aagtttctat
241 ttacagattt acgaatagta tatagagaca ataatccata tggcgtgtgt attatgtgcc
301 tacgcttttt atctaagata agtgaatata ggcattatca atattcactg tatgggaaaa
361 cattagaaga gagggtaaaa aaaccattaa gtgaaataac tattagatgt ataatttgtc
421 aaacgccatt atgtcctgaa gaaaaagaaa gacatgttaa tgcaaacaag cgatttcata
481 atattatggg tcgttggaca gggcgctgtt cagagtgttg gagaccccga cctgtgaccc
541 aagtgtaacg tcatgcgtgg agacaaagca actataaaag attatatatt agatctgcaa
601 cctgaaacaa ctgacctaca ctgctatgag caattaggtg acagctcaga tgaggaggat
661 acagatggtg tggaccggcc agatggacaa gcagaacaag ccacaagcaa ttactacatt
721 gtgacatatt gtcacagttg tgatagcaca ctacggctat gcattcatag cactgcgacg
781 gaccttcgta ctctacagca aatgctgttg ggcacattac aagttgtgtg ccccggctgt
841 gcacggctat aaacaaccct gcaatggagg accctgaagg tacagagggc gaaagggagg
901 gatgtacagg ctggtttgaa gtagaggcaa taatagaaaa acaaacagga gataacattt
961 cagaggacga ggatgaaaat gcatatgata gtggaacaga tctaatagat tttatagatg
1021 attcaaatat aaataatgaa caggcagaac atgaggcagc ccgggcattg tttaatgcac
1081 aggaagggga ggatgattta catgctgtgt ctgcagtaaa acgaaagttt acaagcagtc
1141 cggaaagtgc tgggcaagat ggtgtagaaa aacatggtag tccgcgtgca aaacacattt
1201 gtgtaaatac agagtgtgtt ttaccaaaac gcaaaccatg tcacgtagaa gacagcggct
1261 atggcaatag tgaagtggaa gcgcagcaga tggcagacca ggtagacggg caaaatggcg
1321 actggcaaag taacagtagt caatcaagtg gggtgggggc tagtaattca gatgtaagtt
1381 gtactagtat agaggacaat gaggaaaata gtaatagaac gctaaaaagc atacaaaata
1441 ttatgtgcga aaatagcata aaaacaactg tattatttaa atttaaagaa acatatggtg
1501 ttagctttat ggaattagta agaccattta aaagtaatag aagtagttgt acagattggt
1561 gtattatagg aatgggagta acaccatcag ttgcagaagg attaaaagta ttaatacagc
1621 cctatagcat atatgcccat ttgcaatgtt taacatgtga cagaggcgtg cttatactgc
1681 tgctaattag gtttaaatgt ggaaaaaaca gattaacagt gtccaaacta atgtcacagc
1741 tgttaaatat accagaaaca catatggtaa tagaaccacc aaaattacga agtgctacct
1801 gtgcattata ttggtataga acaggtttgt ctaatattag tgaggtatat ggtaccaccc
1861 cagaatggat agaacaacaa acagtattac agcatagctt tgacaatagc atattcgatt
1921 ttggagaaat ggtgcaatgg gcatatgatc atgatataac agatgatagt gacatagcat
1981 ataaatatgc acagttagca gatgtaaata gcaatgctgc agcattccta aaaagcaatt
2041 cgcaagcaaa aatagtaaag gactgtgcaa ccatgtgtag acattataaa cgggcagaaa
2101 gaaaacatat gaatattgga caatggatac agtatagatg tgatagaata gatgatggtg
2161 gagattggag gcctatagta agatttttaa gatatcaaga catagaattt acagcctttt
2221 tagacgcatt taaaaaattt ttaaaaggta tacctaaaaa aaattgttta gtattatatg
2281 gacctgcaaa cacaggaaaa tcatattttg gaatgagttt aattaggttc ttaagtggat
2341 gtgtaatatc ctatgtaaac tcaaaaagcc atttttggct acaaccatta acagatgcaa
2401 aagtgggtat gatagatgat gtaacaccta tatgttggac atatatagat gattatatga
2461 gaaatgcact ggatggaaat gatatatcag tagatgtaaa gcatagagcc ttagtacaaa
2521 taaaatgccc accattaatt ttaacaacaa atacaaatgc aggaacagat cctaggtggc
2581 catatttaca tagtagattg gttgtgtttc atttcaaaaa cccatttcca tttgatgaaa
2641 atggcaatcc tatatatgaa attaacaacg aaaattggaa atcctttttc tcaaggacgt
2701 ggtgcaaatt agatttaata caggaagagg acaaggaaaa cgatggagtc gataccggca
2761 cgtttaaatg cagtgcagga aaaaatacta gatctatacg aagctgatag taatgaccta
2821 aacgcacaaa ttgaacattg gaaattgact cgaatggaat gtgttttgtt ttacaaagca
2881 aaggaactgg gaataactca tataggccac caggtggtgc caccaatggc agtgtctaag
2941 gcaaaggcct gccaagctat tgaactacaa ttggcattgg aggcattaaa caaaacacaa
3001 tatagcacag atggatggac attacaacaa acaagtctag aaatgtggcg tgcagaacca
3061 caaaaatact ttaaaaaaca tgggtataca ataacagtgc aatacgataa tgataaaaac
3121 aatactatgg attatacaaa ctggaaggaa atttatttac ttggtgagtg tgaatgtaca
3181 attgtagaag gacaagtaga ttactatggg ttatattatt ggtgtgatgg agaaaaaata
3241 tattttgtaa aatttagtaa cgatgcaaag caatattgtg taacaggagt atgggaagta
3301 catgtgggtg gtcaggtaat tgtttgtcct gcatctgtat ctagtaacga agtatccact
3361 actgaaactg ctgtccacct atgcaccgaa acctccaaga cctccgcagt gtccgtgggt
3421 gccaaagaca cacacctaca accaccacag aaacgacgac gaccagacgt cacagactcc
3481 agaaacacca agtaccccaa caaccttttg cggggacaac aatccgtgga cagtactaca
3541 cggggactcg tcactgcaac tgagtgcaca aacaaaggac gggttgcaca tacaacttgt
3601 actgcaccta taatacacct aaaaggtgat cctaatagtt taaaatgttt aagatatagg
3661 gtaaaaacac ataaaagttt gtatgttcaa atttcatcta cctggcattg gaccagtaat
3721 gaatgtacaa ataataaact aggtattgta acaataacgt acagtgatga aacacaacgt
3781 caacaatttt taaaaactgt taaaatacca aatactgtgc aagttataca aggtgtcatg
3841 tcattgtgat atttgtacat atgtatatat gtatatgtgt atggtaaaca cccaacacaa
3901 gccaatattg ctgctattgt gtatatataa caatgttagg attatttgta ttttgtttta
3961 ttttgcttat ggtgttttgt gcagtgctta ggccgctctt gctatctata tcggtgtatg
4021 cgcaggtgtt ggtgctggtg cttttgctat gggtatctat tgggtcacca tttaaagtgt
4081 tttttttgta cctactgttt ttatattttc caatgttttg tattcactgt catgcacagt
4141 atttggcaca actgcaataa ctgtacatgt agattggcta catgcatata tgcaaaatat
4201 actttttcac ttttgtagtt tgtctaataa atacttttat attttttaat agcttgtcgc
4261 aatgagatac agacggtcta cacggcacaa acgtgcttct gcaacacagc tatatcaaac
4321 atgcaaagcc tctggcacct gcccccccga tgttattcct aaagtggaag gcacaactat
4381 tgcagatcaa cttttaaaat atggcagcct aggggtgttt tttggaggtt tgggtatagg
4441 tacaggtgca ggctctggtg gtagggcagg ctatgtgcca ttgtccactc gtcctcccac
4501 tagtagtatt accacgtcca ccattcgtcc ccctgtaact gtagaaccca ttggtccctt
4561 agaaccatct atagtttcta tgatagaaga aacaacattt attgagtctg gcgcacctgc
4621 tccatctatt ccatcagcaa cagggtttga tgttacaaca tctgcaaata atactcctgc
4681 aataattaat gtaacatcta taggtgaatc atctgtacaa tcagtttcta cacatttaaa
4741 tcctacattc actgaaccat ctataataca gcccccggca cctgcagaag catctggtca
4801 tgtattgttt tctagtccaa ctattagtac acacacctat gaagaaatcc ctatggatac
4861 atttgttacc tctactgaca gcagcagtgt aacaagtagt acacctattc cagggtctcg
4921 ccctacgaca cgccttggtt tatatagccg tgccacacaa caggttaagg tagtcgaccc
4981 tgcttttatg tcatcaccac agaaattagt aacatataac aatcctgttt ttgagggcgt
5041 tgatacagat gaaactataa tttttgatcg ttcacaactt ttacctgcac cggatcctga
5101 ttttttagac attatagctt tgcataggcc tgcattaacc tctcgaagag gtactgttag
5161 gtttagcagg cttggtaata aggccaccct acgtacacgt agtggaaaac aaattggggc
5221 acgggtacat tattatcatg atattagtcc tatccagcct gctgaagttc aggaagacat
5281 agaattgcaa cctttattac cacagtctgt gtccccttac actattaatg atggtttgta
5341 tgatgtgtat gcagattctt tgcagcaacc cacgtttcac ttaccttcca cactttctac
5401 ccataataat actttcactg tacctattaa tagtggtatt gactttgtat atcaacccac
5461 tatgtccatt gagtcaggtc ctgacattcc attaccttcg ttacccacac atactccttt
5521 tgttcctata gcccctacag ctccatctac atctattatt gttgatggta cagattttat
5581 tttacatcct agttattttt tactacgtcg caggcgtaaa cgttttccat atttttttac
5641 agatgtccgt gtggcggcct agtgaggcca ctgtgtacct gcctcctgta cctgtctcta
5701 aggttgtaag cactgatgag tatgtgtctc gcacaagcat ctattattat gcaggcagtt
5761 ctcgattact aacagtagga catccctatt tttctattaa aaacaccagt agtggtaatg
5821 gtaaaaaagt tttagttccc aaggtgtctg gcctgcaata cagggtattt agaattaaat
5881 tgccggaccc taataaattt ggttttccag atacatcttt ttataaccca gaaacccaaa
5941 ggttggtgtg ggcctgtaca ggcttggaaa ttggtagggg acagccttta ggtgtgggta
6001 ttagtgggca tcctttatta aacaagtttg atgatactga aaccagtaac aaatatgctg
6061 gtaaacctgg tatagataat agggaatgtt tatctatgga ttataagcag actcagttat
6121 gcattttagg atgcaaacct cctataggtg aacattgggg taagggaacc ccttgtaata
6181 ataattcagg aaatcctggg gattgtcctc ccctacagct cattaacagt gtaatacagg
6241 atggggacat ggtagataca ggatttggtt gcatggattt taataccttg caagctagta
6301 aaagtgatgt gcccattgat atatgtagca gtgtatgtaa gtatccagat tatttgcaaa
6361 tggctagcga gccatatggt gacagtttgt tcttttttct tagacgtgag caaatgtttg
6421 ttagacactt ttttaatagg gccggtacct taggtgaccc tgtgccaggt gatttatata
6481 tacaagggtc taactctggc aatactgcca ctgtacaaag cagtgctttt tttcctactc
6541 ctagtggttc tatggtaacc tcagaatccc aattatttaa taaaccgtac tggttacaac
6601 gtgcgcaggg ccacaataat ggcatatgtt ggggcaatca gttgtttgtc acagttgtgg
6661 ataccactcg tagcactaac atgactttat gtgctgaggt taaaaaggaa agcacatata
6721 aaaatgaaaa ttttaaggaa taccttcgtc atggcgagga atttgattta caatttattt
6781 ttcaattgtg caaaattaca ttaacagctg atgttatgac atacattcat aagatggatg
6841 ccactatttt agaggactgg caatttggcc ttaccccacc accgtctgca tctttggagg
6901 acacatacag atttgtcact tctactgcta taacttgtca aaaaaacaca ccacctaaag
6961 gaaaggaaga tcctttaaag gactatatgt tttgggaggt ggatttaaaa gaaaagtttt
7021 ctgcagattt agatcagttt cctttaggta ggaagttttt gttacaggca gggctacagg
7081 ctaggcccaa actaaaacgc cctgcatcat cggccccacg tacctccaca aagaagaaaa
7141 aggttaaaag gtaaccattg tctgttgggt aattgtctgt gtcatgtatg tgttgtgtat
7201 gtcaaacaca ggttaaaagg taaccattgt ttgttatgta attgttttgt gtgtgtactg
7261 tgttgtttgc atgttatgta tgtgtgtgca tgtttgttgt atttgtcagt tcctgtatgt
7321 atgttttgtg tatgtattaa taaagtactg tatttactaa actatttata gtagtcttat
7381 gttatgttat ggttgcaccc acatgagtaa caatacagtt gctcctaatc tattgcatct
7441 cctgccctac cctgtgtccc ctgccctacc ctgtgtccta ctttgttaca ctactaatta
7501 gccttatact ctccattttg taccattttg tactatccac cattttaaat cctaaccgaa
7561 ttcggttggt cttggcacaa ctttggttgt ccttggcaca gtaacaacta tttttatata
7621 agtttcagca aactgcttaa tcctttggtt tcctgcagtc cactggtcta cacttgttgt
7681 cccgcctaaa ctgacttctt gctgactcac aggtcctgca gtgcagctaa acaatacatt
7741 gcctaacatt gcatgtttta aactgctttt aggcacatat tttatttaaa ctttcaatgc
7801 actaattaca gtgttggctt acacaagtac atcctacgcc aaatatgtct tgtaaaacat
7861 gattaaatac tgttactcac caggtgtgca ctacacgacc ggttacggtt accgtaccca
7921 caaccacttt tttttataat ta
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