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EGF/ Urogastrone, Human, Recombinant

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产品概述

产品信息

别名Pro-Epidermal Growth Factor; EGF; Epidermal Growth Factor; Urogastrone
物种Human
表达宿主E.coli
序列信息Asn971-Arg1023
检索号P01133
分子量6.2 kDa
表观分子量11 kDa
生物活性 Measured by its ability to binding EGFR2/ HER2 used funtional ELISA. Measured in a cell proliferation assay using BALB/ c 3T3 cells.The ED50 for this binding effect is 1ug/ ml when EGF 1ug/ ml in a solid phases. The ED50 for this effect is less than

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 200mM NaCl, pH 8.0.
复融Please refer to it for detailed information.

背景介绍

Epidermal Growth Factor (EGF) is a small 53 amino acid residue long Protein that contains three disulfide bridges. It is a small mitogenic Protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. EGF stimulates the growth of various Epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. This Protein shows both strong sequential and functional homology with human type-alpha transforming Growth Factor (hTGF alpha), which is a competitor for EGF Receptor sites.
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