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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Vascular Endothelial Growth Factor Isoform 165; VEGF165 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Ala27-Arg191 |
| 检索号 | P15692-4 |
| 分子量 | 19.1 kDa |
| 表观分子量 | 20 kDa |
产品特性
| 纯度 | >90% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Human Vascular Endothelial Growth Factor (VEGF), also known as VEGF-A and vascular Permeability Factor (VPF), belongs to the platelet-Derived Growth Factor family of cysteine-knot Growth Factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase Receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
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