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IL-21, Human, Recombinant

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产品概述

产品信息

别名Interleukin-21; IL-21; Za11; IL21
物种Human
表达宿主E.coli
序列信息Gln23-Ser155
检索号Q9HBE4
分子量15.6 kDa
表观分子量16 kDa
生物活性 Measured by its ability to binding recombinant human IL2RG used funtional ELISA. Activated

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.
复融Please refer to it for detailed information.

背景介绍

IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
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