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G-CSF/ CSF3 (C-6His), Mouse, Recombinant

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产品概述

产品信息

别名Granulocyte colony-stimulating factor; Csf3; G-CSF
物种Mouse
表达宿主Human Cells
序列信息Val31-Ala208
检索号P09920
分子量19.8 kDa
表观分子量25 kDa
标签C-6His
生物活性 Testing in progress

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4..
复融Please refer to it for detailed information.

背景介绍

Granulocyte colony-stimulating factor (G-CSF) is a Growth Factor and an essential Cytokine which belongs to the IL-6 superfamily. Granulocyte/ macrophage colony-stimulating factors are Cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its Receptor G-CSF-R which belongs to the Cytokine Receptor type I family depends on the interaction of alpha-helical Motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a Cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
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