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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
| 序列信息 | Lys33-Glu262 |
| 检索号 | P07141 |
| 分子量 | 26.0 kDa |
| 表观分子量 | 43 kDa |
| 生物活性 | Measured in a cell proliferation assay using M?NFS?60 mouse myelogenous leukemia lymphoblast cellsThe ED50 for this effect is less than 10 ng/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 0. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Macrophage colony-stimulating factor 1 (M-csf)is a single-pass type I membrane Protein . It is a hematopoietic Growth Factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/ macrophage cell lineage. By interacting with its membrane Receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
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