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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1 |
| 物种 | Rat |
| 表达宿主 | Human Cells |
| 序列信息 | Gln33-Arg254 |
| 检索号 | Q8JZQ0 |
| 分子量 | 25.2 kDa |
| 表观分子量 | 25.2 kDa |
| 生物活性 | Testing in progress |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | In general, recombinant Proteins are provided as lyophilized powder which are shipped at ambient temperature. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Rat Macrophage colony-stimulating factor 1 (MCSF,CSF1) is a single-pass type I membrane Cytokine. It is a hematopoietic Growth Factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory Chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipo Protein clearance.
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