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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
别名 | Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1 |
物种 | Human |
表达宿主 | E.coli |
序列信息 | Ser113-Ala271 |
检索号 | P01583 |
分子量 | 18 kDa |
表观分子量 | 17 kDa |
生物活性 | Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is less than 50 pg/ mL. |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
内毒素 | < 1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. |
复融 | Please refer to it for detailed information. |
背景介绍
Interleukin-1 alpha (IL1α) is a Cytokine member of the Interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface Receptors but are distinct Proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
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