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IL-1α/ IL1F1, Mouse, Recombinant

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产品概述

产品信息

别名Interleukin-1 Alpha; IL-1 Alpha; Il1a
物种Mouse
表达宿主E.coli
序列信息Ser115-Ser270
检索号P01582
分子量18.0 kDa
表观分子量16 kDa
生物活性 Measured in a cell proliferation assay using mouse D10S cells.The ED50 for this effect is less than 20 pg/ mL.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl, 200mM NaCl, pH 8.0.
复融Please refer to it for detailed information.

背景介绍

Mouse Interleukin-1 (IL-1) designates two Proteins, IL-1α and IL-1β, which are the products of distinct genes, but recognize the same cell surface Receptors. IL-1α and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both Proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The Proteins are synthesized as 31 kDa precursors that are subsequently cleaved into Proteins with molecular weights of approximately 17.5 kDa.
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