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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interleukin-1 beta; Catabolin; IL1F2; IL1B. |
| 物种 | Human |
| 表达宿主 | E.coli |
| 序列信息 | Ala117-Ser269 |
| 检索号 | P01584 |
| 分子量 | 17.5 kDa |
| 表观分子量 | 17 kDa |
| 生物活性 | Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is typically 142 pg/ mL |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide Cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast Growth Factor activity. IL-1 Proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
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