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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2 |
| 物种 | Rabbit |
| 表达宿主 | E.coli |
| 序列信息 | Val77-Leu235 |
| 检索号 | P04924 |
| 分子量 | 17.59 kDa |
| 表观分子量 | 18 kDa |
| 生物活性 | Measured in a cytotoxicity assay using L?929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is less than 20 pg/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Tumor necrosis factor alpha (TNFα) is the prototypic Ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of Receptors TNF-R1 (TNF Receptor type 1,p55R) and TNF-R2 (TNF Receptor type 2,p75R). TNFα is a pleiotropic Cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
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