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Interferon γ/ IFN-γ/ IFNG, Human, Recombinant

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产品概述

产品信息

别名Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG
物种Human
表达宿主Human Cells
序列信息Gln24-Gln166
检索号P01579
分子量16.8 kDa
表观分子量16&20-25 kDa
生物活性 Measured by a viral resistance assay using VSV-WISH cells.Specific Activity is greater than 1.5×10^7 IU/ mg.

产品特性

纯度>90% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
复融Please refer to it for detailed information.

背景介绍

IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.
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