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热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

产品概述

产品信息

别名	Leukemia Inhibitory Factor; LIF; Differentiation-Stimulating Factor; D Factor; Melanoma-Derived LPL Inhibitor; MLPLI; Emfilermin; LIF; HILDA
物种	Human
表达宿主	E.coli
序列信息	Ser23-Phe202
检索号	P15018
分子量	19.7 kDa
表观分子量	18 kDa
生物活性	Measured by the M1 cell differentiation assay.The ED50 for this effect is less than 0.8 ng/ ml

产品特性

纯度	>95% as determined by reducing SDS-PAGE.
内毒素	< 1.0 EU per μg as determined by LAL test.
保存	Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输	The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 0.02% Tween 20, pH 7.4.
复融	Please refer to it for detailed information.

背景介绍

Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production in vivo. Human and murine mature LIF exhibit a 78% sequence identity at the amino acid level. Human LIF is equally active on human and mouse cells. Murine LIF is approximately 1000 fold less active on human cells than human LIF.