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TGFβ2/ TGFB2, Human, Recombinant

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产品概述

产品信息

别名Transforming Growth Factor beta-2; TGFB2; Polyergin; G-TSF; Glioblastoma-Derived T-cell suppressor factor; Cetermin; BSC-1 cell growth inhibitor; TGF-beta-2
物种Human
表达宿主Human Cells
序列信息Ala303-Ser414
检索号P61812
分子量12.7 kDa
表观分子量12 kDa
生物活性 Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T?cells.The ED50 for this effect is less than 15 ng/ ml.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
复融Please refer to it for detailed information.

背景介绍

Transforming Growth Factor beta-2 (TGF-β2) is a secreted Protein which belongs to the TGF-beta family. It is known as a Cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated Protein. It is known to suppress the effects of Interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
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