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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
别名 | Transforming Growth Factor beta-2; TGFB2; Polyergin; G-TSF; Glioblastoma-Derived T-cell suppressor factor; Cetermin; BSC-1 cell growth inhibitor; TGF-beta-2 |
物种 | Human |
表达宿主 | Human Cells |
序列信息 | Ala303-Ser414 |
检索号 | P61812 |
分子量 | 12.7 kDa |
表观分子量 | 12 kDa |
生物活性 | Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T?cells.The ED50 for this effect is less than 15 ng/ ml. |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
内毒素 | < 1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
制剂 | Lyophilized from a 0.2 μm filtered solution of 4 mM HCl. |
复融 | Please refer to it for detailed information. |
背景介绍
Transforming Growth Factor beta-2 (TGF-β2) is a secreted Protein which belongs to the TGF-beta family. It is known as a Cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated Protein. It is known to suppress the effects of Interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
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