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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 Protein; transforming Growth Factor beta-1 |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
| 序列信息 | Ala279-Ser390 |
| 检索号 | P04202 |
| 分子量 | 12.8 kDa |
| 表观分子量 | 14 kDa |
| 生物活性 | Measured by its ability to inhibit IL-4-dependent proliferation of TF?1 human erythroleukemic cells.The ED50 for this effect is less than 1 ng/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 50mM Glycine,150mM NaCl,pH 2.5. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Transforming Growth Factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide Growth Factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric Receptor complex, consisting of a Ligand binding TGF-β Receptor type II (TβR-II), and a TGF-β Receptor type I (TβR-I). Signal transduction from the Receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
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