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产品名称
起订量
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库存(PCS)
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产品概述
产品信息
别名 | Tumor necrosis factor Receptor superfamily member 17; TNFRSF17; B-cell maturation Protein; CD269 |
物种 | Human |
表达宿主 | Human Cells |
序列信息 | Met1-Ala54 |
检索号 | Q02223 |
分子量 | 32.8 kDa |
表观分子量 | 38-40 |
产品特性
纯度 | >95% as determined by reducing SDS-PAGE. |
内毒素 | < 1.0 EU per μg as determined by LAL test. |
保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
制剂 | Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4. |
复融 | Please refer to it for detailed information. |
背景介绍
B cell maturation Protein (BCMA) is a type III membrane Protein which belongs to the TNF Receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) Protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
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