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TARC/ CCL17 (C-6His), Human, Recombinant

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产品概述

产品信息

别名ABCD-2; CC Chemokine TARC; C-C Motif Chemokine 17; CCL17; Chemokine (C-C Motif) Ligand 17; MGC138273; SCYA17MGC138271; small inducible Cytokine subfamily A (Cys-Cys), member 17; Small-inducible Cytokine A17; T cell-directed CC Chemokine; TARC; TARCA-
物种Human
表达宿主Human Cells
序列信息Ala24-Ser94
检索号Q92583
分子量9.1 kDa
表观分子量13 kDa

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
复融Please refer to it for detailed information.

背景介绍

C-C Motif Chemokine 17 (CCL17) is a novel CC Chemokine, it belongs to the intercrine beta (Chemokine CC) family. CCL17 is expressed at high levels in thymus, and at a lower level in lung, colon, and small intestine. CCL17 is also transiently expressed in stimulated peripheral blood mononuclear cells. Among CC Chemokine family members, CCL17 has approximately 24 - 29% amino acid sequence identity with RANTES, MIP-1 alpha, MIP-1 beta, MCP-1, MCP-2 and MCP-3. CCL17 has been identified to be Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. CCL17 plays a role in T-cell development in thymus and in trafficking and activation of mature T-cells.
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