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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | C-C Motif Chemokine 28; Mucosae-Associated Epithelial Chemokine; MEC; Protein CCK1; Small-Inducible Cytokine A28; CCL28; SCYA28 |
| 物种 | Human |
| 表达宿主 | E.coli |
| 序列信息 | Ile20-Tyr127 |
| 检索号 | Q9NRJ3 |
| 分子量 | 12.49 kDa |
| 表观分子量 | 15 kDa |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel Chemokine that shares the most homology with CCL27/ CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan Receptor) is also the Receptor for CCL27/ CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
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