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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Tumor necrosis factor Receptor superfamily member 8; CD30L Receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Phe19-Lys379 |
| 检索号 | P28908 |
| 分子量 | 65.2 kDa |
| 表观分子量 | 90-120 kDa |
| 标签 | C-Fc |
| 生物活性 | Testing in progress |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
CD30, also known as TNFRSF8, is a cell membrane Protein of the tumor necrosis factor Receptor family, which regulates proliferation/ apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its Ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
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