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Fractalkine/ CX3CL1 (C-6His), Human, Recombinant

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产品概述

产品信息

别名Fractalkine; C-X3-C Motif Chemokine 1; CX3C Membrane-Anchored Chemokine; Neurotactin; Small-Inducible Cytokine D1; CX3CL1; FKN; NTT; SCYD1
物种Human
表达宿主Human Cells
序列信息Gln25-Arg339
检索号P78423
分子量34.4 kDa
表观分子量70 kDa
标签C-6His
生物活性 Testing in progress

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
复融Please refer to it for detailed information.

背景介绍

Human Fractalkine (CX3CL1) is a member of the CX3C family of Chemokines. Human Fractalkine contains both Chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long Protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.
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