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FGF-17 (C-6His), Human, Recombinant

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产品概述

产品信息

别名Fibroblast Growth Factor 17; FGF-17; FGF17
物种Human
表达宿主Human Cells
序列信息Thr23-Thr216
检索号O60258
分子量22.6 kDa
表观分子量31 kDa
标签C-6His
生物活性 Measured in a cell proliferation assay using Balb/ 3T3 mouse embryonic fibroblast cells.The ED50 for this effect is less than 15 ug/ ml.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融Please refer to it for detailed information.

背景介绍

Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding Growth Factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition, FGF17 stimulates the proliferation and activation of cells that express FGF Receptors.
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