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FGF-7/ KGF, Human, Recombinant

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产品概述

产品信息

别名Fibroblast Growth Factor 7; FGF-7; Heparin-binding Growth Factor 7; HBGF-7; Keratinocyte Growth Factor; FGF7; KGF
物种Human
表达宿主E.coli
序列信息Cys32-Thr194
检索号P21781
分子量19.1 kDa
表观分子量23 &38 kDa
生物活性 Measured by its ability to bind Human FGFR3 in functional ELISA. The ED50 for this effect is less than 5 ug/ ml.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB,pH8.0,l50mM NaCl.
复融Please refer to it for detailed information.

背景介绍

Fibroblast Growth Factor 7 (FGF7) is a secreted Protein which is mainly located in epithelial cells and belongs to the heparin-binding Growth Factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific Growth Factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
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