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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Fibroblast Growth Factor 8; Androgen-induced Growth Factor; Heparin-binding Growth Factor 8; AIGF; HBGF-8; FGF-8B |
| 物种 | Human |
| 表达宿主 | E.coli |
| 序列信息 | Gln23-Arg244 |
| 检索号 | P55075-4 |
| 分子量 | 27.7 kDa |
| 表观分子量 | 30 kDa |
| 标签 | N-6His |
| 生物活性 | Measured in a cell proliferation assay using BALB/ c 3T3 cells.The ED50 for this effect is less than 0.5 ug/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT,pH 7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Fibroblast Growth Factor 8 (FGF-8) is a member of the fibroblast Growth Factor family. It is discovered as a Growth Factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
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