暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Tumor necrosis factor Ligand superfamily member 18; TNFSF18; Activation-inducible TNF-related Ligand; Glucocorticoid-induced TNF-related Ligand; AITRL; GITRL; TL6 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Glu74-Ser199 |
| 检索号 | Q9UNG2 |
| 分子量 | 15.3 kDa |
| 表观分子量 | 16 &18 kDa |
| 标签 | C-6His |
| 生物活性 | Testing in progress |
产品特性
| 纯度 | >90% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
TNFSF18 is a single-pass type II membrane Protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 Cytokine binds to TNFRSF18/ AITR/ GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation of NF-kappa-B. As Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. It also regulates migration of monocytes from the splenic reservoir to sites of inflammation.
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
