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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interleukin-36 Alpha; FIL1 Epsilon; Interleukin-1 Epsilon; IL-1 Epsilon; Interleukin-1 Family Member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Ser21-Gln356 |
| 检索号 | Q9NPH3 |
| 分子量 | 39.75 kDa |
| 表观分子量 | 67 kDa |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the Interleukin-1 Receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-Ligand binding accessory component of the Receptors for IL1α, IL1βand IL33. IL-1RAcP mediates Interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 Receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to Interleukins by associating with soluble IL1R1 and enhancing Interleukin-binding to the decoy Receptor.
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