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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interleukin-2 Receptor subunit beta; IL2RB; IL-2 Receptor subunit beta; IL-2R subunit beta; High affinity IL-2 Receptor subunit beta; CD122 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Ala27-Asp239 |
| 检索号 | P14784 |
| 分子量 | 25.6 kDa |
| 表观分子量 | 35-40 kDa |
| 标签 | C-6His |
| 生物活性 | Testing in progress |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Human IL-2RB, also known asInterleukin-2 Receptor subunit beta,is the Receptor for Interleukin-2. IL2 Receptor complex is involved in Receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 Receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane Protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for Receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family Protein tyrosine kinase although it lacks apparent catalytic Motifs.
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