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IGFBP1/ IBP-1 (C-6His), Human, Recombinant

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产品概述

产品信息

别名Insulin-Like Growth Factor-binding Protein 1; IBP-1; IGF-binding Protein 1; IGFBP-1; Placental Protein 12; PP12
物种Human
表达宿主Human Cells
序列信息Ala26-Asn259
检索号P08833
分子量26.1 kDa
表观分子量30-35 kDa

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融Please refer to it for detailed information.

背景介绍

Insulin-Like Growth Factor-binding Protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature Protein. IGF-binding Proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface Receptors. Promotes cell migration. Regulation of Insulin-Like Growth Factor (IGF) transport and uptake by Insulin-Like Growth Factor Binding Proteins (IGFBPs).
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