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IFNα4/ IFNA4, Human, Recombinant

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产品概述

产品信息

别名Interferon alpha-4; Interferon alpha-4B; Interferon alpha-76; Interferon alpha-M1; IFNA4
物种Human
表达宿主Human Cells
序列信息Cys24-Asp189
检索号P05014
分子量20.4 kDa
表观分子量20 kDa
标签C-6His
生物活性 Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus.The ED50 for this effect is 2-10pg/ mL.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.
复融Please refer to it for detailed information.

背景介绍

Interferon stimulates the production of two enzymes: a Protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted Protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
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