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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interferon gamma Receptor 1; IFNGR1; CDw119; CD119 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Glu18-Ser245 |
| 检索号 | P15260 |
| 分子量 | 28.7 kDa |
| 表观分子量 | 40-50 kDa |
| 标签 | C-6His |
| 生物活性 | Measured by its ability to inhibit rhIFN-γ mediated protection of WISH cells infected with vesicular stomatitis virus (VSV).The ED50 for this effect is typically 2-8 μg/ mL. |
产品特性
| 纯度 | >90% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Store at < -20℃, stable for 6 months after receipt.Please minimize freeze-thaw cycles. |
| 运输 | The product is shipped on dry ice or blue ice. Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Interferon gamma Receptor 1 (IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane Protein which belongs to the type II Cytokine Receptor family. IFNGR1 is phosphorylated at Ser/ Thr residues after translation. IFNGR1 is a Receptor for interferon gamma, two Receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
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