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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interleukin-1 Receptor-like 1; Protein ST2; DER4; ST2; T1 |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Lys19-Phe328 |
| 检索号 | Q01638-2 |
| 分子量 | 36.0 kDa |
| 表观分子量 | 60 kDa |
| 标签 | C-6His |
| 生物活性 | Measured by its binding ability in a functional ELISA. 2. Immobilized recombinant human IL33 at 10 μg/ mL (100 μl/ well) can bind biotinylated human IL1RL1 (isoform A) with a linear range of 0.032-8 μg/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Interleukin 1 Receptor-like 1 (IL1RL1) is a member of the Interleukin-1 Receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a Receptor for Interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ ERK1 and/ or MAPK1/ ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 Cytokine production, it directly implicated in the progression of cardiac disease.
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