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IL-8/ CXCL8 (Ala23-Ser99), Human, Recombinant

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产品概述

产品信息

别名Interleukin-8; IL-8; C-X-C Motif Chemokine 8; Emoctakin; Granulocyte Chemotactic Protein 1; GCP-1; Monocyte-Derived Neutrophil Chemotactic Factor; MDNCF; Monocyte-Derived Neutrophil-Activating Peptide; MONAP; Neutrophil-Activating Protein 1; NAP-1; P
物种Human
表达宿主E.coli
序列信息Ala23-Ser99
检索号P10145
分子量8.9 kDa
表观分子量11 kDa
生物活性 Measured by its ability to activate chimeric Receptor and induce reporter gene expression in HEK293 cell line used Splite TEV activity detection platform.The ED50 for this effect is less than 15 ng/ mL.

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复融Please refer to it for detailed information.

背景介绍

Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of Chemokines. It is one of the initial Cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.
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