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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Thrombopoietin; C-mpl Ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; Myeloproliferative leukemia virus oncogene Ligand; THPO |
| 物种 | Human |
| 表达宿主 | Human Cells |
| 序列信息 | Ser22-Gly353 |
| 检索号 | P40225 |
| 分子量 | 37.3 kDa |
| 表观分子量 | 70-90 kDa |
| 标签 | N,C-6His |
| 生物活性 | Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cellsThe ED50 for this effect is less than 10 ng/ ml. |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH 8.0. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Thrombopoietin (TPO) is a glyco Protein hormone which belongs to the EPO/ TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific Cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
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