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Eotaxin-2/ CCL24, Mouse, Recombinant

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产品概述

产品信息

别名C-C Motif Chemokine 24; Ccl24; Eosinophil chemotactic Protein 2; Eotaxin-2; Small-inducible Cytokine A24; Scya24
物种Mouse
表达宿主E.coli
序列信息Val27-Val119
检索号Q9JKC0
分子量10.3 kDa
表观分子量12 kDa
生物活性 Testing in progress

产品特性

纯度>95% as determined by reducing SDS-PAGE.
内毒素< 1.0 EU per μg as determined by LAL test.
保存Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融Please refer to it for detailed information.

背景介绍

Mouse CCL24 is a secreted Protein, which is a member of the CC Chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor Protein, shares approximately 58% amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, eosinophils and can bind to CCR3. LPS and IL4 also differentially regulate the expression of Ccl24 in monocytes and macrophages.
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