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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品概述
产品信息
| 别名 | Interleukin-15 Receptor subunit alpha; Il15ra; sIL-15 Receptor subunit alpha |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
| 序列信息 | Gly33-Lys205 |
| 检索号 | Q60819 |
| 分子量 | 45.5 kDa |
| 表观分子量 | 60-90 kDa |
| 标签 | C-Fc |
| 生物活性 | Measured by its ability to block human IL-15-induced proliferation of CTLL?2 mouse cytotoxic T cells.The ED50 for this effect is less than 10 ng/ ml. |
产品特性
| 纯度 | >90% as determined by reducing SDS-PAGE. |
| 内毒素 | < 1.0 EU per μg as determined by LAL test. |
| 保存 | Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| 运输 | The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 复融 | Please refer to it for detailed information. |
背景介绍
Mouse Interleukin-15 Receptor subunit alpha, also known as Il15ra, is a high-affinity Receptor for Interleukin-15. Il15ra associates as a heterotrimer with the IL-2 Receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the Receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.
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