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E Protein (E.coli，N-6His)GV-P00271-1mg￥ 8000.001
产品简介
| Purity | Greater than 85% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0 |
| Shipping | The product is shipped on dry ice pack. |
| Storage | Reconstituted protein solution should be stored at ≤ -20°C. |
| Background | Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction. |
| 规格 | 1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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