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Recombinant Human Pro-neuregulin-1/NRG1?beta 1(MetGV-P00443-10ug¥ 620.001
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Recombinant Human Pro-neuregulin-1/NRG1?beta 1(MetGV-P00443-50ug¥ 1176.001
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Recombinant Human Pro-neuregulin-1/NRG1?beta 1(MetGV-P00443-500ug¥ 6400.001
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Recombinant Human Pro-neuregulin-1/NRG1?beta 1(MetGV-P00443-1mg¥ 9600.001
产品简介
中文名称 | Recombinant Human Pro-neuregulin-1/NRG1?beta 1(Met1-Lys246) |
Known as | Pro-neuregulin-1;Neuregulin-1 beta 1;NRG1-beta 1;HRG1-beta 1 ECD;EGF;NRG1; GGF; HGL; HRGA; NDF; SMDF; |
Derived from | E.coli |
Purity | Greater than 90% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HClPlease aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | neuregulin-1 (heregulin-1,NRG1) is a member of neuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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