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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140bGV-P00509-10ug¥ 620.001
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Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140bGV-P00509-50ug¥ 1800.001
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Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140bGV-P00509-500ug¥ 10160.001
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Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140bGV-P00509-1mg¥ 14000.001
产品简介
中文名称 | Recombinant Human PDGF R beta/PDGFRB/PDGFRβ/CD140b |
Known as | Platelet-Derived Growth Factor Receptor Beta; PDGF-R-Beta; PDGFR-Beta; Beta Platelet-Derived Growth Factor Receptor; Beta-Type Platelet-Derived Growth Factor Receptor; CD140 Antigen-Like Family Member B; Platelet-Derived Growth Factor Receptor 1; PDGFR-1; CD140b; PDGFRB; PDGFR; PDGFR1 |
Derived from | Human Cells |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. |
Background | Platelet-Derived Growth Factor Receptor β (PDGFR-β) is a member of the protein kinase superfamily and CSF-1/PDGF receptor subfamily. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. The extracellular region of the PDGF receptor-β consists of five immunoglobulin-like domains while the intracellular part is a tyrosine kinase domain. In addition to being a potent mitogen for cells of mesenchymal origin, PDGF has also been shown to be a potent chemoattractant for mesenchymal cells, mononuclear cells, and neutrophils and has been reported to be important in the modification of cellular matrix constituents. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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