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库存(PCS)
起订数量
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Recombinant Human LILRB2/CD85d/ILT4/Leukocyte ImmuGV-P00603-10ug¥ 844.001
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Recombinant Human LILRB2/CD85d/ILT4/Leukocyte ImmuGV-P00603-50ug¥ 2520.001
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Recombinant Human LILRB2/CD85d/ILT4/Leukocyte ImmuGV-P00603-500ug¥ 13520.001
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Recombinant Human LILRB2/CD85d/ILT4/Leukocyte ImmuGV-P00603-1mg¥ 18800.001
产品简介
中文名称 | Recombinant Human LILRB2/CD85d/ILT4/Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2/Lir-2/LIR2/MIR10 |
Known as | Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2; LIR-2; Leukocyte Immunoglobulin-Like Receptor 2; CD85 Antigen-Like Family Member D; Immunoglobulin-Like Transcript 4; ILT-4; Monocyte/Macrophage Immunoglobulin-Like Receptor 10; MIR-10; CD85d; LILRB2; ILT4; LIR2; MIR10 |
Derived from | Human Cells |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa transmenbrane segment, and a 116 aa cytoplasmic domain. LIR-2 binds to Classical MHCI proteins. Ligation of LIR-2 incluces Tyr phosphorylation within its cytoplasmic ITIMs, a requirement for association with SHP-1. LIR-2 mediates tolerogenic DC-induced CD4+ T cell energy in vitro and in vivo. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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