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Recombinant Human Heat-Responsive Protein 12/Hrsp1GV-P00728-10ug¥ 956.001
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Recombinant Human Heat-Responsive Protein 12/Hrsp1GV-P00728-50ug¥ 2628.001
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Recombinant Human Heat-Responsive Protein 12/Hrsp1GV-P00728-500ug¥ 13520.001
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Recombinant Human Heat-Responsive Protein 12/Hrsp1GV-P00728-1mg¥ 18800.001
产品简介
中文名称 | Recombinant Human Heat-Responsive Protein 12/Hrsp12 |
Known as | Ribonuclease UK114; 14.5 kDa Translational Inhibitor Protein; p14.5; Heat-Responsive Protein 12; UK114 Antigen Homolog; HRSP12; PSP |
Derived from | E.coli |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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