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Recombinant Human GFER/HPO/FAD-linked sulfhydryl o48T¥ 11
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Recombinant Human GFER/HPO/FAD-linked sulfhydryl o96T¥ 11
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Recombinant Human GFER/HPO/FAD-linked sulfhydryl oGV-P01149-10ug¥ 1064.001
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Recombinant Human GFER/HPO/FAD-linked sulfhydryl oGV-P01149-50ug¥ 3000.001
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Recombinant Human GFER/HPO/FAD-linked sulfhydryl oGV-P01149-500ug¥ 13520.001
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Recombinant Human GFER/HPO/FAD-linked sulfhydryl oGV-P01149-1mg¥ 18800.001
产品简介
Known as | FAD-linked sulfhydryl oxidase ALR;GFER;Augmenter of liver regeneration;hERV1;Hepatopoietin;GFER;ALR;HERV1;HPO |
Derived from | E.coli |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 4mM HCl.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. |
Background | GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. Isoform 2 may act as an autocrine hepatotrophic growth factor promoting liver regeneration. GFER could also induce the expression of S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases (ODC). S-adenosylmethionine decarboxyl-ase and ornithine decarboxylases play an important role in the synthesis of polyamines. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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人Ⅰ型胶原α1(COL1α1)试剂盒(ELISA)说明书
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