Recombinant Human OGG1/N-glycosylase/DNA lyase-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

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热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

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上海极威生物科技有限公司　公司地址:上海市崇明县长兴镇潘园公路1800号2号楼9703室

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Known as	N-Glycosylase/DNA Lyase; 8-Oxoguanine DNA Glycosylase; DNA-(Apurinic or Apyrimidinic Site) Lyase; AP Lyase; OGG1; MMH; MUTM; OGH1
Derived from	E.coli
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.
Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3’ to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.
规格	10ug50ug500ug1mg

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